Date: Thu, 2 Nov 2006 15:22:16 -0600
Reply-To: nagyd**At_Symbol_Here**MSNOTES.WUSTL.EDU
Sender: DCHAS-L Discussion List <DCHAS-L**At_Symbol_Here**LIST.UVM.EDU>
From: nagyd**At_Symbol_Here**MSNOTES.WUSTL.EDU
Subject: flammable solvents in clean room
Looking for some help on limited use of flammable solvents in a class
10,000 clean room.

The proposal is to use hexane, ethyl acetate, and ethanol (absolute) for an
extraction and
purification project that would last approx. 1 week, would involve approx
30 L total of the 3
solvents and here's the catch....there's no fume hood in the clean room.
The process would
involve mixing in 4-8L poly bottles, filtering using house vac, cleaning
with ethanol and oven drying
the cleaned glassware, distillation of hexane/ethyl acetate mixture, then
do another extraction with ethanol,
distill the ethanol, finally drying the flask with its solid contents in a
vac oven (house vac).

All this to be done at bench top in a positive-pressurized clean room.

I have suggested the use of a ductless fume hood provided that the charcoal
filter can adequately handle
the 3 solvents. Obviously, everything has to be kept closed at all times
except when adding or removing.

But I would welcome other thoughts, suggestions, and experiences.


Dennis R. Nagy, CHMM
Washington University
Campus Box 8229
St. Louis, MO 63110
(314) 747-3172
(314) 362-1995 (fax)

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