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Subject: Re HF use
Date: Tue, 6 Jan 2009 15:29:08 -0500
Author: Rigel Lustwerk
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Date: Tue, 6 Jan 2009 21:21:12 +0000
Reply-To: porterjb**At_Symbol_Here**COMCAST.NET
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From: porterjb**At_Symbol_Here**COMCAST.NET
Subject: Re: HF Response
In-Reply-To: <1490684846.144831231276654459.JavaMail.root**At_Symbol_Here**sz0129a.westchester.pa.mail.comcast.net>
The DuPont MSDS for HF is copied below. Stay safe......Jim
The MSDS format adheres to the standards and regulatory requirements
of the United States and may not meet regulatory requirements
in other countries.
DuPont Page 1
Material Safety Data Sheet
----------------------------------------------------------------------
Hydrofluoric Acid (10-48%)
6373CR Revised 14-MAY-2005
----------------------------------------------------------------------
----------------------------------------------------------------------
CHEMICAL PRODUCT/COMPANY IDENTIFICATION
----------------------------------------------------------------------
Material Identification
CAS Number : 7664-39-3
Molecular Weight : 20.01
CAS Name : Hydrogen Fluoride
Tradenames and Synonyms
Hydrogen Fluoride
HF
Fluorohydric Acid
Fluoric Acid
HF in Aqueous Solution
Company Identification
MANUFACTURER/DISTRIBUTOR
DuPont Fluoroproducts
1007 Market Street
Wilmington,
Delaware
19898
PHONE NUMBERS
Product Information : 1-(800)-441-7515
Transport Emergency : 1-(800)-424-9300
Medical Emergency : 1-(800)-441-3637
----------------------------------------------------------------------
COMPOSITION/INFORMATION ON INGREDIENTS
----------------------------------------------------------------------
Components
Material CAS Number %
*Hydrogen Fluoride 7664-39-3 10-48
Water 7732-18-5 52-90
* Disclosure as a toxic chemical is required under Section 313 of
Title III of the Superfund Amendments and Reauthorization Act of 1986
and 40 CFR part 372.
6373CR DuPont Page 2
Material Safety Data Sheet
----------------------------------------------------------------------
HAZARDS IDENTIFICATION
----------------------------------------------------------------------
Potential Health Effects
SKIN
Depending on the concentration and duration of exposure, skin
contact may produce pain, redness of skin, and deep slow-healing
burns. Acid concentrations of more than 50% in water (including
anhydrous hydrogen fluoride) cause immediate severe, throbbing
pain and a whitish discoloration of the skin. Burns may be
excruciatingly painful, deep-seated and slow healing. Hydrogen
Fluoride aqueous solutions from 20% to 50% may produce pain,
swelling, and blisters which may be delayed up to 8 hours.
Hydrogen Fluoride solutions of less than 20% cause almost no
immediate pain on contact but may cause delayed serious injury 12
to 24 hours later; latent skin burns with necrosis can occur even
at concentrations of at least 2%. Healing of skin burns caused by
concentrated Hydrogen Fluoride may be prolonged, and extensive
scarring may result.
In some forms, fluoride can readily penetrate the skin and deep
tissue causing destruction of soft tissue and decalcification of
bone. Tissue destruction and neutralization of HF may proceed for
days. HF can be absorbed through the skin in toxic amounts.
EYES
Mild effects of Hydrogen Fluoride exposure include rapid onset of
eye irritation with discomfort, tearing, or blurring of vision.
More severe effects, which may result from even minor Hydrofluoric
acid splashes, include sloughing of the surface of the eye,
swelling of various structures of the eye, corrosion of the eye
with corneal or conjunctival ulceration and cell death due to lack
of blood supply. Potentially permanent clouding of the eye
surface may develop immediately or after several days. Permanent
loss of vision can occur.
INGESTION
Ingestion of Hydrogen Fluoride may cause corrosive injury to the
mouth, throat and esophagus. Inflammation of the stomach with
bleeding occurs commonly. Nausea, vomiting, diarrhea, and
abdominal pain may occur. Systemic effects are likely. An
acid-base imbalance can occur after acute ingestion. Pulmonary
aspiration may lead to respiratory complications. Hydrogen
Fluoride ingestion may cause progressive damage to the esophagus
and stomach for weeks after ingestion. Persistent narrowing of
the esophagus may result. Death may occur.
INHALATION
6373CR DuPont Page 3
Material Safety Data Sheet
(HAZARDS IDENTIFICATION - Continued)
Inhaled Hydrogen Fluoride mist or vapor initially affects the
nose, throat, and eyes. Mild clinical effects include
mucous-membrane irritation and inflammation, cough, and narrowing
of the bronchi. Severe clinical effects include an almost
immediate narrowing and swelling of the throat, causing upper
airway obstruction and lung injury that may evolve rapidly or may
be delayed in onset for 12 to 36 hours. These severe effects can
include choking and coughing; severe throat irritation followed by
fever, chills, difficulty in breathing, cyanosis and pulmonary
edema, accumulation of fluid in the lungs, constriction of the
bronchi, and partial or complete lung collapse can occur. Death
may occur. Pulmonary effects can result even from Hydrogen
Fluoride splashes on the skin due to inhalation of fumes from the
area splashed.
ADDITIONAL EFFECTS
Overexposure by inhalation or skin contact may lead to systemic
effects. These effects are due to Hydrogen Fluoride=E2=80=99s penetration
of cells and its rapid dissociation into hydrogen and fluoride
ions. The dissociated fluoride can penetrate and migrate into
tissue and bind with calcium primarily, but also magnesium,
sodium, and potassium. Local bone demineralization, systemic
deficiency of calcium (hypocalcemia) and magnesium, and excess
potassium can occur. Hypocalcemia can lead to life-threatening
cardiac arrhythmias. The adverse effect of the fluoride ion may
progress for several days after exposure.
Prolonged exposure to Hydrogen Fluoride vapor can cause fluorosis
which may also result in weight loss, brittle bones, anemia,
weakness and stiffness of joints, and discoloration of the teeth
when exposure occurs during tooth formation.
Carcinogenicity Information
None of the components present in this material at concentrations
equal to or greater than 0.1% are listed by IARC, NTP, OSHA or ACGIH
as a carcinogen.
----------------------------------------------------------------------
FIRST AID MEASURES
----------------------------------------------------------------------
Compound-Specific First Aid & Notes to Physicians
Speed in removing exposed personnel from contaminated area and in
removing HF from skin or eyes is of primary importance. First aid
must be started immediately, within seconds, in all cases of
contact with hydrofluoric acid in any form. All potentially
exposed personnel should be trained in first aid care for HF
burns. First aid actions should be planned before beginning work
with HF. Calcium gluconate gel should be readily accessible in
areas where HF exposure potential exists.
6373CR DuPont Page 4
Material Safety Data Sheet
(FIRST AID MEASURES - Continued)
Medical assistance should be obtained promptly for all affected
persons. The doctor should be informed in detail of the accident.
HF differs from other acids in that the fluoride ion readily
penetrates skin, causing destruction of deep tissue layers
including bone. Unlike the action of other acids, which are
rapidly neutralized, this process may continue for days.
HF contaminated oils and tars may require additional first aid
steps because water washing may not completely remove the oil or
tar. Sites that have potential for HF contaminated oils or tars
should develop appropriate procedures to remove the oil/tar from
the skin to allow treatment.
The following are DuPont=E2=80=99s first aid recommendation for HF
exposures, however, modifications may be required to comply with
local or state medical board regulatory requirements.
SKIN CONTACT:
IMMEDIATELY shower with large quantities of water, within seconds
after contact or suspected contact, and completely remove all
clothing while in shower (remove goggles last). FLUSH SKIN
THOROUGHLY WITH WATER FOR 5 MINUTES. Flushing with water
thoroughly for 5 minutes is sufficient to effectively remove HF
from skin. Additional flushing time is unnecessary and will delay
further treatment.
Apply calcium gluconate (2.5%) gel at burn site or area of
contamination by rubbing in continuously. Wear impervious gloves.
Examination and treatment by a physician is recommended as quickly
as feasible. It may be necessary to transport patient to nearest
hospital emergency room. Remember that concentrated HF causes
immediate pain, BUT DILUTE HF SOLUTIONS MAY NOT CAUSE REDNESS,
BURNING OR PAIN UNTIL SEVERAL MINUTES OR EVEN HOURS HAVE ELAPSED.
EYE CONTACT:
IMMEDIATELY flush eyes with large quantities of water for 5
MINUTES while holding the eyelids apart. Trained personnel should
apply calcium gluconate 1% (no stronger) by continuous drip. If
skills are available at the scene, a Morgan Theraupeutic Lens can
be used to irrigate the eyes with a calcium gluconate 1% solution.
THE EYES WILL REQUIRE FURTHER TREATMENT-- SEE NOTES TO
PHYSICIAN--"EYE CONTACT".
VAPOR INHALATION:
IMMEDIATELY remove the patient to an uncontaminated atmosphere.
Call a physician. Administer oxygen as soon as possible. Trained
personnel should provide calcium gluconate, 2.5% solution, by
nebulizer with patient in sitting position. Keep patient warm.
6373CR DuPont Page 5
Material Safety Data Sheet
(FIRST AID MEASURES - Continued)
Patients not breathing
If exposed person is not breathing, do not give mouth to mouth
resuscitation; instead use an Ambu-bag. Do not administer any
liquids or solids to an unconscious person.
INGESTION:
DO NOT induce vomiting. If patient is conscious, give water
orally to dilute followed by antacid or milk. Seek medical
assistance immediately. Call a physician. Throat burns may cause
severe swelling and require a tracheotomy (opening the windpipe).
The patient should be admitted to the hospital and carefully
attended.
MEDICAL SUPPLIES:
The following materials have been found to be useful and effective
in the treatment of hydrogen fluoride burns, and should be on hand
at the First Aid Station:
o Calcium gluconate gel - 2.5%. This gel is prepared by mixing 1
standard ampule (10 mL, 10%) of USP calcium gluconate with 1-ounce
of water soluble lubricant (e.g., K-Y Lubricating Jelly, Johnson &
Johnson).
The shelf life of the gel has not been determined. A periodic
replacement period should be specified (ie., annually). Storage
of gel has limitations and refrigeration may help. Avoid freezing
the gel as calcium may precipitate out and reduce its
effectiveness.
o Calcium gluconate 10% (standard ampules).
o One percent calcium gluconate in normal, sterile saline
solution. Make by mixing 1 standard ampule per 90 mL of saline
solution.
o 2.5% calcium gluconate in normal, sterile saline solution. Make
by mixing 1 standard ampule per 30 mL of saline solution.
Solution (both 1% and 2.5%) shelf-life has not been determined. A
periodic replacement period should be specified (ie., every 6
months).
o Milk of magnesia or other liquid antacid.
o 99% pure USP medical oxygen with regulator and mask.
o Impervious gloves.
o Nebulizer.
o Blanket.
o Shower facilities.
o Ambu bag.
o Nasal cannula units and Morgan Therapeutic Lens (for eye
irrigation).
NOTES TO PHYSICIANS:
Choice of therapy following first aid measures is at the
discretion of attending physician. Selection of the best
treatment will depend on the following factors:
6373CR DuPont Page 6
Material Safety Data Sheet
(FIRST AID MEASURES - Continued)
o Concentration and temperature of the HF.
o Degree and extent of the burn.
o Duration of exposure.
o Areas of the body affected.
o Elapsed time since exposure.
o First aid measures taken before physician=E2=80=99s arrival.
o Age and clinical history of patient.
o General condition of the patient.
The following methods, using materials listed under MEDICAL
SUPPLIES, have been effective in treatment of HF burns. Methods
are broken down by routes of exposure. Minor exposures are
limited exposures to HF liquid and vapor. Major exposures are
extensive exposures to HF liquid and vapor and all cases of
combined routes of exposure, e.g., skin and inhalation exposures.
Patients suffering suspected face or chest skin exposure should be
assumed to have incurred inhalation exposure also. Be certain
that the patient has been properly decontaminated.
In all cases of major exposure by HF, hypocalcemia may be present,
therefore, calcium levels must be determined immediately upon
arrival at the hospital. During hospitalization calcium levels
should be monitored frequently. If possible, blood should be
drawn for serum calcium in site medical facility and sent to the
hospital with the patient.
Cardiac monitoring (EKG) is necessary (hypocalcemia causes
prolonged Q-T interval and may cause cardiac rhythm
abnormalities). Renal and liver function should be monitored.
In major inhalation exposure, pulmonary edema or edema of upper
airway may occur. Blood gases should be monitored accordingly.
SKIN CONTACT: Care should be taken to see that personnel who
apply the gel, especially on the initial application, wear medical
gloves to prevent skin contamination with HF and the development
of hand burns.
Topically applied Calcium Gluconate Gel (2.5%) must be rubbed into
all burn areas continuously until pain has completely subsided,
but not longer than 30 minutes. Calcium gluconate gel should not
be used until after thorough and complete washing of the skin with
water for 5 minutes. If some relief of pain is not obtained
within 20-30 minutes, consider calcium gluconate topical
injections using stainless steel needle.
6373CR DuPont Page 7
Material Safety Data Sheet
(FIRST AID MEASURES - Continued)
Severe Skin Burns:
When there is evidence of skin penetration as in second or third
degree burns or for large burns, a 5% calcium gluconate solution
may be injected using a small gauge needle (no. 30) by
infiltrating the skin and subcutaneous tissues in the same manner
as injection of any local anesthetic. The standard ampoule of 10%
calcium gluconate for intravenous use must be diluted to 5% by
mixing with an equal amount of normal sterile saline. Care should
be taken to avoid overdosing with calcium. Do not inject more
than 0.5 mL per square centimeter of affected skin surface. No
local infiltration of anesthetic should be used, but in the case
of severe burns, regional or general anesthesia may be considered.
DO NOT INJECT CALCIUM CHLORIDE to treat skin burns.
In cases of overexposure due to HF, as in skin burns of greater
than approximately 2 square inches (13 cm2) in area, hypocalcemia
may be present. Therefore, systemic administration of calcium
gluconate may be necessary. Infusions can be repeated until serum
calcium, EKG or symptoms improve. Frequent monitoring of serum
calcium, cardiac, renal, and hepatic functions is necessary.
Treat hypomagnesemia with 1-2 grams of magnesium.
HAND BURNS: The treatment for hand burns require expert
assistance; consult a hand surgeon. Intra arterial calcium
infusions have been successfully used to treat HF hand exposures.
Calcium gluconate in very small doses can be injected into the
fingers. In some cases, burr holes must be drilled in the nail or
the nail must be split or removed to permit adequate contact with
the sequestering agent. Local anesthesia may be required, but be
aware that it may interfere with determining the adequacy of
treatment. Care must be used because multiple injections into the
fingers can lead to pressure necrosis. Patients whose skin has
compromised integrity may have an increased risk of infection
after multiple injections of calcium gluconate. Consider the use
of antibiotic creams such as Silvadene or Garamycin in these cases.
EYE CONTACT: Immediate washing of the eyes with large quantities
of water for 5 minutes should be followed by continuous drip of 1%
calcium gluconate (no stronger) in normal, sterile saline using a
nasal prong or Morgan Lens. Up to 500 mL over 1-2 hours may be
used. A topical anesthetic can minimize the tendency of the
eyelid to close and facilitate inserting an irrigation lens. If
exposure was minor, perform visual acuity testing and examine the
eyes for corneal damage using fluorescein and a slit lamp. An eye
specialist (ophthalmologist) should be consulted immediately.
6373CR DuPont Page 8
Material Safety Data Sheet
(FIRST AID MEASURES - Continued)
VAPOR INHALATION: Persons suspected of having had HF exposure by
inhalation should immediately be given 100% oxygen by mask or
catheter. As soon as possible (as precautionary treatment), they
should be administered (in the sitting position and utilizing a
nebulizer) 2.5% calcium gluconate solution by inhalation for 20
minutes. All those suspected of HF exposure and who experience
signs and/or symptoms of respiratory irritation should be
considered as strong candidates for admission to an intensive care
unit for careful observation during the first 24-48 hours.
Delayed pulmonary edema is likely in patients with burns of the
skin of face or neck.
Patient should be carefully watched for edema of the upper airway
with respiratory obstruction and the airway maintained by
tracheotomy or endotracheal intubation if necessary. The
administration of respiratory care should be very closely
supervised and most likely includes continued administration of
2.5% calcium gluconate by inhalation. Toxicity from pulmonary
absorption of fluoride ion may rapidly develop in the liver and
kidneys and may require more energetic measures of control, up to
and including hemodialysis, particularly if the blood urea
nitrogen and potassium levels rise. Supportive care is necessary
for all organ systems.
INGESTION: THIS SITUATION IS LIFE THREATENING. DO NOT INDUCE
VOMITING AND DO NOT USE ACTIVATED CHARCOAL. Refer to first aid
measures as described. Extreme throat swelling may cause airway
obstruction, which may require endotracheal intubation or
cricothyroidotomy.
----------------------------------------------------------------------
FIRE FIGHTING MEASURES
----------------------------------------------------------------------
Flammable Properties
Will not burn.
HF (particularly in dilute aqueous solutions) will attack
most metals, releasing potentially explosive hydrogen gas.
Follow appropriate National Fire Protection Association
(NFPA) codes.
Extinguishing Media
Water Fog, Dry Chemical, CO2.
Fire Fighting Instructions
Keep upwind. If there is any possibility of direct contact,
wear full acid suit with hood, boots and self-contained
breathing apparatus. Run-off from fire control may cause
pollution; neutralize with lime.
6373CR DuPont Page 9
Material Safety Data Sheet
----------------------------------------------------------------------
ACCIDENTAL RELEASE MEASURES
----------------------------------------------------------------------
Safeguards (Personnel)
NOTE: Review FIRE FIGHTING MEASURES and HANDLING (PERSONNEL)
sections before proceeding with clean-up. Use appropriate
PERSONAL PROTECTIVE EQUIPMENT during clean-up.
Accidental Release Measures
Evacuate area and keep upwind until gas has dispersed.
Enter contaminated area only with full protective equipment
and self-contained breathing apparatus. Dike spill. Dilute
with water fog (direct addition of water or alkali causes
heat and violent spattering). Neutralize with lime. Do not
flush to sewer. Comply with Federal, State, and Local
regulations on reporting releases.
WATER MITAGATION: The use of water sprays on HF vapors from
a release have been found to be effective in removing HF
from the air, and thus lowering the amount leaving the spill
area. HF removal efficiencies of 25% - 90% have been
demonstrated at water to HF ratios of 6:1 to 60:1. Do NOT
spray water directly on the leak source as increased
corrosion may occur making the leak larger.
DuPont Emergency Exposure Limits (EEL) are established to
facilitate site or plant emergency evacuation, and specify
airborne concentrations of brief durations which should not
result in permanent adverse health effects or interfere with
escape. These limits are used in conjunction with
engineering controls/monitoring and as a aid in planning for
episodic releases and spills. For more information on the
applicability of EEL=E2=80=99s, contact DuPont.
The DuPont Emergency Exposure Limit (EEL) for Hydrofluoric
Acid are:
100 ppm ceiling for 1 minute
50 ppm for up to 10 minutes
20 ppm for up to 60 minutes
AMERICAN INDUSTRIAL HYGIENE ASSOCIATION (AIHA) EMERGENCY
RESPONSE PLANNING GUIDELINES (ERPG):
The off-site exposure limits (sixty minutes) for
hydrofluoric acid as specified by the AIHA are:
ERPG 1,2 ppm - The maximum airborne concentration below
which it is believed that nearly all individuals could be
exposed for up to one hour without experiencing other than
mild, transient adverse health effects or without perceiving
a clearly defined objectionable odor.
ERPG 2, 20 ppm - The maximum airborne concentration below
6373CR DuPont Page 10
Material Safety Data Sheet
(ACCIDENTAL RELEASE MEASURES - Continued)
which it is believed that nearly all individuals could be
exposed for up to one hour without experiencing or
developing irreversible or other serious health effects or
symptoms which could impair an individual=E2=80=99s ability to take
protective action.
ERPG 3, 50 ppm - The maximum airborne concentration below
which it is believed that nearly all indivudals could be
exposed for up to one hour without experiencing or
developing life-threatening health effects.
----------------------------------------------------------------------
HANDLING AND STORAGE
----------------------------------------------------------------------
Handling (Personnel)
Do not breathe vapor or mist. Do not get in eyes, on skin, or on
clothing. Wash thoroughly after handling.
Keep containers closed.
Storage
Keep away from heat, sparks, and flame. Keep container
tightly closed. Drainage facilities should be constructed
for containment of small spills.
NOTE:
HF may react with steel, forming iron fluorides. During
storage tank cleaning, iron fluoride particles may be
released which, if inhaled, may cause lung damage. Iron
fluoride scale reacts with water to produce HF, which may
cause delayed burns when skin or eye contact occurs.
----------------------------------------------------------------------
EXPOSURE CONTROLS/PERSONAL PROTECTION
----------------------------------------------------------------------
Engineering Controls
Use only with ventilation sufficient to keep vapor
concentrations below the exposure limit. Use forced draft
ventilation and scrubbers for fume control.
Personal Protective Equipment
EYE/FACE:
Wear chemical splash goggles. In addition, where the
possibility exists for face contact due to splashing or
spraying of the material, wear a full-length face shield/
chemical splash goggle combination or an acid hood.
RESPIRATORS:
6373CR DuPont Page 11
Material Safety Data Sheet
(EXPOSURE CONTROLS/PERSONAL PROTECTION - Continued)
If exposure limits may be exceeded, wear NIOSH
approved respiratory protection.
PROTECTIVE CLOTHING:
Where there is potential for skin contact, have available
and wear as appropriate: acid resistant rubber gauntlet
gloves, boots, and acid resistant jacket and pants. If
there is any possibility of direct contact, wear a full
acid suit of acid resistant material with hood,
gloves, boots, and full-face air supplied respirator. The
highest degree of protection, used for large leaks or in an
emergency situation, is provided by a fully encapsulating
acid resistant suit (one piece construction) with a
self-contained breathing apparatus.
Protective clothing and equipment should not be worn or
carried outside of the operating area. Wash protective
clothing and equipment under a safety shower after exposure,
or suspected exposure, to hydrofluoric acid.
Note: In an emergency leak situation, avoid contacting
fully encapsulating suits with a liquid stream of HF because
permature suit failure may occur.
# Exposure Guidelines
Exposure Limits
Hydrofluoric Acid (10-48%)
PEL (OSHA) : 3 ppm, 8 Hr. TWA, as F
TLV (ACGIH) : 0.5 ppm, 8 Hr. TWA, as F
Ceiling 2 ppm, as F
AEL * (DuPont) : 3 ppm, 15 minute TWA
* AEL is DuPont=E2=80=99s Acceptable Exposure Limit. Where governmentally
imposed occupational exposure limits which are lower than the AEL
are in effect, such limits shall take precedence.
----------------------------------------------------------------------
PHYSICAL AND CHEMICAL PROPERTIES
----------------------------------------------------------------------
Physical Data
Boiling Point : 104-108 C (219-226 F)
Melting Point : -11 to -36 C (12 to -33 F)
Solubility in Water : Infinitely soluble
Odor : Acrid
Form : Fuming, liquid
Color : Clear, colorless
Specific Gravity : 1.17-1.18
pH : ~2 2% aqueous solution
6373CR DuPont Page 12
Material Safety Data Sheet
----------------------------------------------------------------------
STABILITY AND REACTIVITY
----------------------------------------------------------------------
Chemical Stability
Stable, if stored in proper (steel) container.
Incompatibility with Other Materials
Incompatible with arsenic trioxide, phosphorous pentoxide,
ammonia, calcium oxide, sodium hydroxide, sulfuric acid,
vinyl acetate, ethylenediamine, acetic anhydride.
Decomposition
Decomposes by reaction with metals, liberates hydrogen gas.
On heating to decomposition, could yield toxic fumes of
fluorides. Attacks glass and other silicon containing
compounds. Reacts with silica to reduce silicon
tetrafluoride, a hazardous colorless gas. Evaporation would
produce hydrogen fluoride gas.
Polymerization
Polymerization will not occur.
----------------------------------------------------------------------
TOXICOLOGICAL INFORMATION
----------------------------------------------------------------------
Animal Data
Hydrogen Fluoride
Inhalation 1 hour LC50: 2300 ppm in rats
Skin absorption 1-2 minute ALD: 500 mg/kg in mice
Hydrogen Fluoride is corrosive to skin and eyes in tests on
animals.
Animal inhalation studies at very high concentrations resulted in
eye, mucous membrane and skin irritation, corneal opacities,
respiratory distress, pulmonary congestion, and hemorrhage. Other
short term studies show lung, heart, liver, kidney, spleen, and
brain damage. Repeated exposure caused an uptake of fluoride into
bones and teeth, corneal opacities, irritation or ulceration of
skin, respiratory irritation and edema, anemia, weight loss, and
pathological changes in the liver, lungs and kidneys. Long-term
exposure to low concentrations by inhalation resulted in fatty
deposits in the liver, high plasma concentrations of cholesterol,
kidney damage and disturbances in the process involved in
calcification. Fluoride was taken up by bones and teeth.
Single dermal exposure to low concentrations resulted in severe
burns. Other studies show increased fluoride content in the
serum, lungs, liver and kidneys, and mortality.
6373CR DuPont Page 13
Material Safety Data Sheet
(TOXICOLOGICAL INFORMATION - Continued)
An 18 month study in animals demonstrated no carcinogenic
activity. Studies show that Hydrogen Fluoride causes heritable
genetic damage in insects, but no test data are available for
mammals. No acceptable animal test reports are available to
define developmental or reproductive toxicity.
----------------------------------------------------------------------
ECOLOGICAL INFORMATION
----------------------------------------------------------------------
Ecotoxicological Information
Aquatic Toxicity
96 hour LC50 in fish (species not specfied): 1-50 ppm
----------------------------------------------------------------------
DISPOSAL CONSIDERATIONS
----------------------------------------------------------------------
Waste Disposal
Comply with Federal, State, and Local regulations. If
approved, may be flushed to sewer to waste treatment plant,
or transferred to a disposal contractor.
----------------------------------------------------------------------
TRANSPORTATION INFORMATION
----------------------------------------------------------------------
Shipping Information
DOT/IMO
Proper Shipping Name : Hydrofluoric Acid, with not more than 60
percent strength
Hazard Class : 8
UN No. : UN 1790
Subsidiary Hazard Class : 6.1 (Poison)
Packing Group : II
Reportable Quantity : 100 lb
----------------------------------------------------------------------
REGULATORY INFORMATION
----------------------------------------------------------------------
U.S. Federal Regulations
TSCA Inventory Status : Reported/Included.
TITLE III HAZARD CLASSIFICATIONS SECTIONS 311, 312
Acute : Yes
Chronic : Yes
Fire : No
Reactivity : Yes
Pressure : No
6373CR DuPont Page 14
Material Safety Data Sheet
(REGULATORY INFORMATION - Continued)
LISTS:
SARA Extremely Hazardous Substance -Yes
CERCLA Hazardous Substance -Yes
Toxic Chemical -Yes
CANADIAN WHMIS CLASSIFICATION
D-1A; E
Country_specific Regulations
----------------------------------------------------------------------
OTHER INFORMATION
----------------------------------------------------------------------
NFPA, NPCA-HMIS
NFPA Rating
Health : 4
Flammability : 0
Reactivity : 0
NPCA-HMIS Rating
Health : 3
Flammability : 0
Reactivity : 2
Personal Protection rating to be supplied by user depending on use
conditions.
Additional Information
For further information, see DuPont=E2=80=99s Hydrofluoric Acid
"Data Sheet" and Properties, Uses, Storage, and Handling
Bulletin.
----------------------------------------------------------------------
The data in this Material Safety Data Sheet relates only to the
specific material designated herein and does not relate to use in
combination with any other material or in any process.
Responsibility for MSDS : MSDS Coordinator
> : DuPont Fluoroproducts
Address : Wilmington, DE 19898
Telephone : (800) 441-7515
# Indicates updated section.
This information is based upon technical information believed to be
reliable. It is subject to revision as additional knowledge and
experience is gained.
End of MSDS
----- Original Message -----
From: porterjb**At_Symbol_Here**COMCAST.NET
To: DCHAS-L**At_Symbol_Here**LIST.UVM.EDU
Sent: Tuesday, January 6, 2009 8:41:10 AM GMT -05:00 US/Canada Eastern
Subject: Re: [DCHAS-L] HF Response
HF is extremely hazardous and any direct exposure (skin or inhalation) can
be life threatening . DuPont makes HF and has excellent safety and treatmen
t guides and procedures. Go to their website and send a request for the inf
o via their contact e-mail.=C2=A0=C2=A0 Stay safe...Cheers, Jim
----- Original Message -----
From: "Suzanne Hamm " < suzanne **At_Symbol_Here** POLYMERSOLUTIONS .COM>
To: DCHAS-L**At_Symbol_Here**LIST. UVM . EDU
Sent: Tuesday, January 6, 2009 8:11:41 AM GMT -05:00 US/Canada Eastern
Subject: [DCHAS-L] HF Response
Does anyone have a procedure for response to an HF exposure or safety guide
lines for use of HF? Some of our chemists like to use this to clean glasswa
re when nothing else will work. We have some guidelines in place now but wo
uld like to make sure everything is covered.
Thank you,
Suzanne Hamm
Safety Manager
Polymer Solutions Incorporated
2903C Commerce Street
Blacksburg , Virginia 24060
(540) 961-4300 x (201), phone
(540) 961-5778, fax
www . PolymerSolutions .com , web-site
=C2=A0
Polymer Solutions Incorporated is ISO/ IEC 17025 accredited, FDA Registered
, and DEA Licensed.
=C2=A0
PROPRIETARY NOTICE
This e-mail and its attachments contain proprietary information that is int
ended only for the individual or entity indicated. =C2=A0If you are not the
intended recipient, you are hereby notified that the disclosure, copying,
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