Date: Fri, 20 Nov 2009 11:01:12 -0500
Reply-To: DCHAS-L Discussion List <DCHAS-L**At_Symbol_Here**LIST.UVM.EDU>
Sender: DCHAS-L Discussion List <DCHAS-L**At_Symbol_Here**LIST.UVM.EDU>
From: Keifer.Leonard**At_Symbol_Here**EPAMAIL.EPA.GOV
Subject: Re: Toxicity testing on chemicals
In-Reply-To: <9E60FE388C7BA0479931FDB57C5363200152591284**At_Symbol_Here**>
If these are new monomers you may want to investigate whether or not
they should be submitted to EPA as Premanufacture Notice.

Here is a link to the OPPTS Harmonized Health Testing Guidelines.

  From:       Jessica Whiteley                                                                       
  To:         DCHAS-L**At_Symbol_Here**LIST.UVM.EDU                                                                                                    
  Date:       11/20/2009 10:50 AM                                                                                                     
  Subject:    [DCHAS-L] Toxicity teting on chemicals                                                                                  


My company is looking to perform some toxicity testing on some of our
monomers for the dental industry (not FDA testing).  Does anyone know of
good companies that perform such testing?

We had also looked at this particular test
ISO 7405:2008 contains a cytotoxicity test method common to the dental

Are there any others that are recommended?  Is this a good test to have
done?  I appreciate any insight you may have in this area.


Jessica Whiteley
Manager of Regulatory Affairs/Chemical Engineer
Manager of Quality Control
610-521-3800 ext 121

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