Date: Tue, 14 Sep 2010 14:31:56 -0700
Reply-To: p3wt3r**At_Symbol_Here**
Sender: DCHAS-L Discussion List <DCHAS-L**At_Symbol_Here**LIST.UVM.EDU>
From: Todd <p3wt3r**At_Symbol_Here**CHARTER.NET>
Subject: Re: Shelf Life of PEG 400 used for Phenol First Aid Treatment
In-Reply-To: <C3E98B533BBA314490DC0D1C18E02317095A55EF**At_Symbol_Here**pb01msx.wgipb.local>

For most medical products, including those used in first aid, you need to d
o studies to determine expiration - or purchase material which has been tes
ted and bears an expiration. So if you're using NF PEG400 as a starting mat
erial in a presealed container, you could store it through the expiration d
ate unless it has been opened.  OTOH if you are packaging it, you will like
ly need to perform or contract the Sterility Testing of the product, and po
ssibly have an FDA and State Board of Pharmacy license to manufacture medic
al use materials.

Todd Perkins
Safety Director
Airgas Mid America

> -----Original Message-----
> From: DCHAS-L Discussion List [mailto:DCHAS-L**At_Symbol_Here**LIST.UVM.EDU]On
> Behalf Of
> Larry D. McLouth
> Sent: Tuesday, September 14, 2010 2:11 PM
> To: DCHAS-L**At_Symbol_Here**LIST.UVM.EDU
> Subject: [DCHAS-L] Shelf Life of PEG 400 used for Phenol
> First Aid
> Treatment
> We're developing first aid procedures for phenol and
> phenol/chloroform.=A0 
> This involves decontaminating affected areas with
> polyethylene glycol 
> (400 MW) instead of water.=A0 Flushing with water may
> spread phenol to 
> other parts of the body.
> Because of its expense, we plan to buy larger quantities of
> PEG 400 and 
> repackage it into 1 L nalgene bottles.=A0 This, along
> with other supplies 
> (gauze pads, gloves, disposable coveralls - for modesty,
> etc.) will be 
> put in light tight buckets.=A0 The buckets will be
> stored in labs at room 
> temperature.
> My question is about the shelf life of the PEG after it has
> been opened 
> and repackaged.=A0 Chemical suppliers report shelf lives
> from 1 to 2 
> years.=A0 But I believe this applies to PEG intended for
> manufacturing and 
> research applications. 
> Does anyone have experience with the use of PEG 400 for 1st
> aid 
> treatment who can recommend a shelf life?=A0 Literature
> citations (if they 
> exist) would be much appreciated.
> Regards
> Larry
> = 

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