Date: Tue, 11 Oct 2011 14:49:07 -0700
Reply-To: DCHAS-L <DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU>
Sender: DCHAS-L Discussion List <dchas-l**At_Symbol_Here**>
From: Chuck Cooper <cooperc**At_Symbol_Here**PDX.EDU>
Subject: Re: DCHAS-L] Toxic chemicals/toxins from the culture
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We would treat the culture dishes as a hazardous waste because of the wortmannin which is listed as highly toxic. If I was disposing of a large ongoing stream of similar material I would look at it more closely (TCLP it,  incinerate as bio-waste possibly)

On Oct 11, 2011, at 12:05 PM, Tilak Chandra wrote:

Dear CHAS Colleagues:

What are the best practices for disposing the toxic chemicals/toxins from the
culture? Autoclaving is standard practice for deactivating the cells; however
some chemicals cannot be deactivated using autoclaving. Specifically, the
cultures have been treated with wortmanin and p-nitrophenyl-B-D-gluco
pyranoside. I cannot find any information on disposal for these. Is there is any
certain method for the inactivation/disposal of such system?

Thank you very much.


Tilak Chandra, Ph.D.
Chemical Safety Specialist
Facilities Planning & Management
Environment, Health and Safety
30 East Campus Mall
Madison, WI 53715
Ph. 608-890-0255
FAX 608-262-6767

Chuck Cooper
Senior Advisor for Research Safety
Environmental Health and Safety
Portland State University

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