From: Debbie M. Decker <dmdecker**At_Symbol_Here**UCDAVIS.EDU>
Subject: Re: [DCHAS-L] HPLC solvent disposal
Date: Tue, 4 Oct 2016 18:38:21 +0000
Reply-To: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**PRINCETON.EDU>
Message-ID: BLUPR08MB53437885D414B929DBD9A2BC8C50**At_Symbol_Here**

A good rule of thumb is flammable solvent greater than about 20% in water probably has enough of a flash point for it to meet "flammable" characteristics.


Yeah - this is hazardous waste and should be managed as such.


Good luck!



Debbie M. Decker, CCHO, ACS Fellow

Immediate Past Chair, Division of Chemical Health and Safety

University of California, Davis




Birkett's hypothesis: "Any chemical reaction

that proceeds smoothly under normal conditions,

can proceed violently in the presence of an idiot."



We have a research group that wants to begin a HPLC project using tetrafluoroacetic acid/acetonitrile mix (diluted to 40% in water) as the solvent. The student working on the project has used this procedure at another institution and said they dumped the waste solvent down the drain. Really? I thought this would still have some characteristic hazard. Does anyone else have experience with this mixture, and how do you dispose of it properly?

Laurie M. Yoder

Assistant Professor of Chemistry and Chemical Hygiene Officer

Eastern Mennonite University

1200 Park Road

Harrisonburg, VA 22802


--- This e-mail is from DCHAS-L, the e-mail list of the ACS Division of Chemical Health and Safety. For more information about the list, contact the Divisional secretary at

Previous post   |  Top of Page   |   Next post

The content of this page reflects the personal opinion(s) of the author(s) only, not the American Chemical Society, ILPI, Safety Emporium, or any other party. Use of any information on this page is at the reader's own risk. Unauthorized reproduction of these materials is prohibited. Send questions/comments about the archive to
The maintenance and hosting of the DCHAS-L archive is provided through the generous support of Safety Emporium.