From: Samuella Beth Sigmann <sigmannsb**At_Symbol_Here**APPSTATE.EDU>
Subject: Re: [DCHAS-L] Papers on risks of scaling up reactions
Date: Tue, 25 Sep 2018 11:38:51 -0400
Reply-To: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**PRINCETON.EDU>
Message-ID: 5dbf8006-e63c-03cf-4cf7-3af730d89856**At_Symbol_Here**appstate.edu
In-Reply-To


You could use the Texas Tech incident that the CSB investigated.

https://www.csb.gov/texas-tech-university-chemistry-lab-explosion/
Sammye


On 9/25/2018 11:04 AM, Jeffrey R. Cogswell wrote:

Hello

I??m currently working on a safety talk about RAMP and decided to include a section on ??RAMPing up Reactions??

It was discussed at ACS that scaling up reactions is a under-stated danger in many chemistry laboratories.

Does anyone have any suggestion for articles that talks about or quantifies the risks of increasing the yield in chemical reactions?

For example: https://ac.els-cdn.com/S1871553213006178/1-s2.0-S1871553213006178-main.pdf?_tid=672cf49d-0170-4ff1-8b06-85bc88bda807&acdnat=1537887055_4baf3ea46cec9ef7b4cb51c2aba76bf8 I found very informative and it would be great to find more sources.

Thanks

Jeffrey R. Cogswell, Ph.D.

Chemical Inventory and Laboratory Resource Center Technician, EHS

37 Dewey Field Road, HB 6216

Hanover, New Hampshire 03755

http://www.dartmouth.edu/~ehs/

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Samuella B. Sigmann, MS, NRCC-CHO

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