From: Monique Wilhelm <mwilhelm**At_Symbol_Here**UMICH.EDU>
Subject: [DCHAS-L] TBE Buffer: Conflicting Hazard Clarification
Date: Thu, 10 Feb 2022 11:08:49 -0500
Reply-To: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**Princeton.EDU>
Message-ID: CAC5HN6ZukyE_os-SwiYZ36JV5PYEPqbC2_DGmm15mC+suXEGpw**At_Symbol_Here**mail.gmail.com


Hi Everyone,

QUESTION: Is the toxic hazard and pictogram required on these labels?

I thought I read somewhere that a label for a mixture does not have to include the hazard of any component less than 1% but cannot easily find it right now. I know carcinogens designations occur at a much lower concentration, 0.001%. So, is the 1% rule true? Does anyone know of this guideline?

My institution uses ChemWatch Gold FFX for SDS and labeling info. Being a biochemist who always made her own solutions, when I looked up TBE info, I looked up each component. Boric acid is listed as a reproductive poison health hazard on its SDS. But, the researcher just looked up TBE buffer and it was listed as non-hazardous. The boric acid is at 0.5% when at 1x concentration, but is often made at 10x concentration and later diluted down. Is it still considered hazardous at these concentrations and require the toxic hazard and pictogram on these labels?

Thank you,
_________________________________________________________
Monique Wilhelm
Lab Manager
CAS, Department of Natural Sciences | The University of Michigan-Flint
303 E. Kearsley St | Room 572 MSB | Flint, MI | 48502-1950
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