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Stay healthy and prosper
NEAL LANGERMAN, Ph.D.
ADVANCED CHEMICAL SAFETY, Inc. (Retired)
5340 Caminito Cachorro
SAN DIEGO CA 92105
+1 (619) 990-4908
From: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**Princeton.EDU> On Behalf Of Augspurger, Ashley
Sent: Friday, June 10, 2022 12:58 PM
To: DCHAS-L**At_Symbol_Here**Princeton.EDU
Subject: Re: [DCHAS-L] [EXTERNAL] [DCHAS-L] Disposing of kanamycin
Hi Jennifer,
I've recently done a lot of research into antibiotic disposal. There are some antibiotics that will breakdown in an autoclave, but most don't which is why they should be discarded as hazardous waste and incinerated. There really aren't any other effective options I've found.
Ashley
Ashley Augspurger, PhD, CIH, CSP
EHS&S Specialist
Chemical Hygiene Officer
Laboratory Biosafety Officer
Safe Science is Good Science
Corteva Agriscience TM
7000 NW 62nd Ave. PO Box 1000 | Johnston, IA 50131
515-535-6382 (w) | 515-350-8387 (c)
One of our researchers uses kanamycin in their antibiotic resistance studies. The total amount used over 10 weeks is about 100mg and would never exceed 200mg. They are working with microgram quantities on a weekly basis.
The NIH Drain Disposal guide suggests kanamycin should be treated as hazardous waste (collected and sent to disposal) Is anyone familiar with alternative disposal for kanamycin? Our concern is the very small amount of kanamycin in the large amount of water and bleach would have a drastic effect on our waste stream.
Is bleach sufficient to render the kanamycin appropriate for drain disposal? I have also seen suggestions that kanamycin be treated with acid to render it inactive and thus okay for drain disposal; but then wonder would neutralizing the acid (to make that appropriate for drain disposal) nullify the acid inactivation?
We do have access to an autoclave, but the NIH guide seems to suggest heat does not render kanamycin safe for the drain.
Your thoughts are appreciated,
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