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Subject: Re: [DCHAS-L] [External] Re: [DCHAS-L] Qiagen kits incident report
Date: Tuesday, June 21, 2022 at 5:37:01 PM
Author: Ralph Stuart <ralph**At_Symbol_Here**rstuartcih.org> 		Next by Date:
Subject: Re: [DCHAS-L] [External] Re: [DCHAS-L] [External] Re: [DCHAS-L] Qiagen kits incident report
Date: Tue, 21 Jun 2022 21:26:09 -0400
Author: Ernest Lippert

From: Shannon Nephew <millersc**At_Symbol_Here**PLATTSBURGH.EDU>
Subject: Re: [DCHAS-L] [External] Re: [DCHAS-L] [External] Re: [DCHAS-L] Qiagen kits incident report
Date: Tue, 21 Jun 2022 19:33:40 -0400
Reply-To: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**Princeton.EDU>
Message-ID: CAEYT+dYLpiLHr3jSk0_n04Pd+-0f9nShHc2Ro3KALjLcQ1DM-A**At_Symbol_Here**mail.gmail.com
In-Reply-To


Hi Ralph,

There is a comment in the enclosed booklet with the kit that has bulleted warning labels, but this is the only one I could find online at the moment...I show the actual booklet we used, when I talk about this in training. I ask if anyone knows what is generated if you mix ethanol (which is in the sample prep waste) with bleach? We then discuss chloroform...
"Do not add bleach or acidic solutions directly to the sample preparation waste. CAUTION: The sample preparation waste contains guanidinium hydrochloride from Buffer BG3, which can form highly reactive compounds when combined with bleach. For more information please consult the appropriate material safety data sheets (MSDS)."

SHANNON C. NEPHEW,
MS, CSM, CCHO
Chemical Hygiene Officer, Hudson Hall Science Complex Building Manager
Science Programs and Facilities Support Professional
Hudson Hall 317
101 Broad Street
Plattsburgh, NY 12901
plattsburgh.edu
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On Tue, Jun 21, 2022 at 5:38 PM Ralph Stuart <ralph**At_Symbol_Here**rstuartcih.org> wrote:
> we flicked the waste tubes into a disposal beaker containing bleach and very shortly, my postdoc and myself felt very lightheaded and dizzy. Once one of us mentioned it and realized we both felt this way, we immediately left the lab and mentally retraced our steps to determine what was going on.

Not a chlorine exposure then?

- Ralph

Ralph Stuart, CIH, CCHO
ralph**At_Symbol_Here**rstuartcih.org

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