Does anyone have experience using Ethyl Acetate in large quantities?

I have run extraction using Ethyl acetate as a primary solvent and some actetylation. 4x 200L reactors. Ventilation in iso8.

Have not had any problems.

What are risks to lab employees with regards to possible inhalation exposure?

I have been asked to contribute as a consultant to a phytochemical extraction facility and there ventilation is c1d2...yet I would guess that is questionable.

Does Ethyl acetate present a major health risk to employees (55 gallon size batches) with likely vapor inhalation exposure?

EPA and SDS data sheets are a bit lacking and contradicting for me to hold a strong stance on this other than full iso8 and limit all exposure with best practices.

I would like to get some personal experience and anecdotal opinions.

Assuming full face respirators are used with organic vapor cartridges, would this not be safe?

Thank you for any input.