From: Michael Kleinman Google Apps <mtkleinm**At_Symbol_Here**UCI.EDU>
Subject: Re: [DCHAS-L] Safety Precautions for high concentrations of NO2 gas.
Date: Mon, 1 Aug 2016 10:35:07 -0700
Reply-To: DCHAS-L <DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU>
Message-ID: 029f01d1ec1b$0c8a08e0$259e1aa0$**At_Symbol_Here**
In-Reply-To <**At_Symbol_Here**>

Nitrogen Dioxide TLV_TWA is 3ppm. That's the time-weighted average level a person can be exposed in the workplace for 8 hr per day with a reasonable expectation of no observed adverse health effects. The Short term (15 min) exposure limit is 5ppm. The Immediately Dangerous to life and Health (ILDH) is 20ppm.

NO2 is a strong oxidant and even brief high level accidental exposures have caused pulmonary edema and death.

Pressurized tank regulators are available with a safety vent which should be arranged to allow any venting to go into a fume hood. I'm sure that Stony Brook has experience safety personnel who can provide relevant advice to you. If you are asking the question, you could be working beyond your area of expertise and should consult with the safety experts at your institution.

Michael T. Kleinman
University of California, Irvine
Department of Medicine
Division of Occupational and Environmental Health
100 Theory Ste 100
Irvine CA 92697-1830

-----Original Message-----
From: DCHAS-L Discussion List [mailto:dchas-l**At_Symbol_Here**MED.CORNELL.EDU] On Behalf Of Roger McClellan
Sent: Monday, August 1, 2016 9:59 AM
Subject: Re: [DCHAS-L] Safety Precautions for high concentrations of NO2 gas.

My experience with NO2 has all been in the environmental health arena. NO2 is nasty. The NAAQS for a 1 hour averaging time is 100ppb. The EPA documentation supporting the NAAQS is substantial and would be worth reviewing. Proceed with appropriate caution in reviewing the entire experimental set up. I would be curious as to the objectives of the experiments and the experience of the investigators and their technical staff.
On Mon, 8/1/16, Sandhya Muralidharan wrote:

Subject: [DCHAS-L] Safety Precautions for high concentrations of NO2 gas.
Date: Monday, August 1, 2016, 9:10 AM

We have a laboratory planning to run experiments with high concentrations of NO2 gas[2500-5000 ppm]. Please advise on any specific specific safety precautions.

Sandhya Muralidharan, PhDLaboratory Safety SpecialistEnvironmental Health & SafetyStony Brook University New York email - sandhya.muralidharan**At_Symbol_Here** phone -

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