From: Roger McClellan <roger.o.mcclellan**At_Symbol_Here**ATT.NET>
Subject: Re: [DCHAS-L] Safety Precautions for high concentrations of NO2 gas.
Date: Mon, 1 Aug 2016 17:17:00 +0000
Reply-To: DCHAS-L <DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU>

Extending the remarks of Eugene, a classic disease syndrome encountered in agriculture is Silo Fillers disease. When corn and other plant material ferments in a confined silo NO2 is formed. There is both an acute phase to the illness, including death, and a chronic phase that is not as well characterized. I remain convinced that a friend of mine who died in his mid- 60s with a diagnosis of idiopathic pulmonary fibrosis actually died as a result of residual injury traceable to multiple exposures to NO2 as a teenager growing up on a farm in the mid west.
I assume the investigators have a well written protocol (reviewed and approved by you) including a description of the containment system for the experimental apparatus.


On Mon, 8/1/16, Eugene Ngai wrote:

Subject: Re: [DCHAS-L] Safety Precautions for high concentrations of NO2 gas.
Date: Monday, August 1, 2016, 9:48 AM


NO2 can cause delayed pulmonary edema, the effects may be delayed up to 72 hrs. The NO2 also causes rapid olfactory fatigue, similar to H2S. Leak testing of the system and gas monitoring is critical

You should have the ATSDR Medical Treatment Guides available for ER

Eugene Ngai

Chemically Speaking LLC

From: DCHAS-L Discussion List [mailto:dchas-l**At_Symbol_Here**] On Behalf Of Sandhya Muralidharan
Sent: Monday, August 1, 2016 12:11 PM
Subject: [DCHAS-L] Safety Precautions for high concentrations of NO2 gas.

Dear All, 

We have a laboratory planning to run experiments with high concentrations of NO2 gas[2500-5000 ppm]. Please advise on any specific specific safety precautions.  




Sandhya Muralidharan, PhD

Laboratory Safety Specialist

Environmental Health & Safety

Stony Brook University 

New York

email - sandhya.muralidharan**At_Symbol_Here** 

phone - 6316329672

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