From: Jeffrey Lewin <jclewin**At_Symbol_Here**MTU.EDU>
Subject: Re: [DCHAS-L] TBE Buffer: Conflicting Hazard Clarification
Date: Tue, 15 Feb 2022 11:21:53 -0500
Reply-To: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**Princeton.EDU>
Message-ID: CAEwQnqg8WBuUvKRKKaTNoTRnV9_kOoZkkF-HXTxawjOeRKnQpA**At_Symbol_Here**mail.gmail.com
In-Reply-To


For what it's worth

Sigma's 10x buffer solution lists:

Pictograms: Health Hazard and Serious Health Hazard
Signal word Danger
Hazard statement(s)
H317 May cause an allergic skin reaction.
H360 May damage fertility or the unborn child.

It took some searching but Fisher has an SDS for 1X; it lists:

This chemical is not considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200)

Label Elements
None required
Hazards not otherwise classified (HNOC)
None identified


Jeff


On Thu, Feb 10, 2022 at 11:13 AM Monique Wilhelm <mwilhelm**At_Symbol_Here**umich.edu> wrote:
Hi Everyone,

QUESTION: Is the toxic hazard and pictogram required on these labels?

I thought I read somewhere that a label for a mixture does not have to include the hazard of any component less than 1% but cannot easily find it right now. I know carcinogens designations occur at a much lower concentration, 0.001%. So, is the 1% rule true? Does anyone know of this guideline?

My institution uses ChemWatch Gold FFX for SDS and labeling info. Being a biochemist who always made her own solutions, when I looked up TBE info, I looked up each component. Boric acid is listed as a reproductive poison health hazard on its SDS. But, the researcher just looked up TBE buffer and it was listed as non-hazardous. The boric acid is at 0.5% when at 1x concentration, but is often made at 10x concentration and later diluted down. Is it still considered hazardous at these concentrations and require the toxic hazard and pictogram on these labels?

Thank you,
_________________________________________________________
Monique Wilhelm
Lab Manager
CAS, Department of Natural Sciences | The University of Michigan-Flint
303 E. Kearsley St | Room 572 MSB | Flint, MI | 48502-1950
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--
Jeff Lewin
Director of Chemical Laboratory Operations
Research Integrity Office
Laboratory Operations
205 Lakeshore Center
Michigan Technological University

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