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From: nagyd**At_Symbol_Here**MSNOTES.WUSTL.EDU
Subject: flammable solvents in clean room
Date: Nov 2, 2006 21:22 UTC
Reply-To: nagyd**At_Symbol_Here**MSNOTES.WUSTL.EDU
In-Reply-To:
Looking for some help on limited use of flammable solvents in a class 10,000 clean room. The proposal is to use hexane, ethyl acetate, and ethanol (absolute) for an extraction and purification project that would last approx. 1 week, would involve approx 30 L total of the 3 solvents and here's the catch....there's no fume hood in the clean room. The process would involve mixing in 4-8L poly bottles, filtering using house vac, cleaning with ethanol and oven drying the cleaned glassware, distillation of hexane/ethyl acetate mixture, then do another extraction with ethanol, distill the ethanol, finally drying the flask with its solid contents in a vac oven (house vac). All this to be done at bench top in a positive-pressurized clean room. I have suggested the use of a ductless fume hood provided that the charcoal filter can adequately handle the 3 solvents. Obviously, everything has to be kept closed at all times except when adding or removing. But I would welcome other thoughts, suggestions, and experiences. Dennis Dennis R. Nagy, CHMM Washington University EHS/OSH Campus Box 8229 St. Louis, MO 63110 (314) 747-3172 (314) 362-1995 (fax) nagy**At_Symbol_Here**wustl.edu