DCHAS-L Archives · Post dated January 19, 2015
From: Wawzyniecki Jr, Stefan <stefan.w**At_Symbol_Here**UCONN.EDU>
Subject: [DCHAS-L] N-100's for nanoparticle formulations.
Date: Jan 19, 2015 21:09 UTC
Reply-To: DCHAS-L <DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU>
In-Reply-To:
Much research is being conducted recently using nanoparticle formulations of chemotherapeutics as well as pain relief meds. NIOSH and the Navy Public Health center have described the use of N 100’s as respiratory protection when working with nanoparticles, and formulations.
My question is-
When evaluating animal research protocols involving formulations on the nanoscale such as chemotherapeutics, is anyone requiring N 100’s when the task isinjecting the medication, as opposed to actually formulating it? One argument I hear from researchers is that their primary concern is autoinjection, which is why they have no problem with wearing gloves, but they would rather not wear a respirator.
Anyone involved in such risk assessment?
-Stefan Wawzyniecki, CIH, CHMM
University of Connecticut