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From: Margaret Rakas <mrakas**At_Symbol_Here**SMITH.EDU>
Subject: Re: [DCHAS-L] LD50 Source Data
Date: Fri, 18 Oct 2019 11:52:12 -0400
Reply-To: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**PRINCETON.EDU>
Message-ID: CAAszpkwQWu1C=ud8pWG3otiUkoBjmSEueoLeVZxssCcaK4_ziw**At_Symbol_Here**mail.gmail.com
In-Reply-To

Demystify: 

Ditto TOXNET. When I was in industry, we had a DABT-certified toxicologist who reviewed our raw materials every two years for target organ effects (and those went on our MSDS's--which I found to be much more informative than the mishmash of prescribed phrases now, IMHO). She told me about TOXNET and that is where I go for tox info...

RTECS is often cited but my understanding is that 'original' data can be very, very difficult to actually find; it was not necessarily peer-reviewed; and now apparently you need a subscription to view it (CDC sells RTECS DB)

So I stick w/Toxnet...
good luck-



On Fri, Oct 18, 2019 at 10:17 AM Keane J. Leitch <kjl44**At_Symbol_Here**cornell..edu> wrote:

Hi Nora,

Check out TOXNET.

Here is a link to one of the search returns for this compound.

https://chem.nlm.nih.gov/chemidplus/rn/872-50-4

best,

Keane Leitch, MPS, CHMM

Safety Manager, Physical Sciences Complex

Cornell University

121 Baker Lab

Ithaca, NY 14853

607-255-8773

kjl44**At_Symbol_Here**cornell.edu

linkedin.com/in/keane-leitch-332bb546

Pronouns: She, Her, Hers

From: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**PRINCETON.EDU> On Behalf Of Nora Dunkel
Sent: Thursday, October 17, 2019 5:06 PM
To: DCHAS-L**At_Symbol_Here**PRINCETON.EDU
Subject: [DCHAS-L] LD50 Source Data

Does anyone know where to find the studies/source data for LD50 values listed in SDSs? I'm specifically looking for studies/data on the reproductive/developmental hazards of methylene chloride and N-methyl-2-pyrrolidone (CAS # 872-50-4). Is there a database somewhere or does each manufacturer keep its source data in-house?

Thanks!

Nora Dunkel

Chemical Safety Officer

Webster University

314 246 2244

661 348 1445

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--
Margaret A. Rakas, Ph.D.
Lab Safety & Compliance Director
Clark Science Center
413-585-3877 (p)

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