From:
Monona Rossol <0000030664c37427-dmarc-request**At_Symbol_Here**LISTS.PRINCETON.EDU>
Subject:
Re: [DCHAS-L] [EXTERNAL] [DCHAS-L] Disposing of kanamycin
Date:
Jun 10, 2022 23:51 UTC
Reply-To:
Monona Rossol
In-Reply-To:
Re: [DCHAS-L] [EXTERNAL] [DCHAS-L] Disposing of kanamycin
Riiiggghhhttt. That depends on where our friend is located in this big country. On all my 80+ building projects I try to talk to the local treatment plant to get their discharge limits for the chemicals I know will be going down the drains. Some have websites with the information all easily available and they will talk to you when you call. But there also are a number of smaller facilities that are secretive about their discharge limits and difficult to deal with. And often I find this is because they have never bothered to calculate some or all of them.
One of these yelled at me that the discharge limits were "none of your damn business."
There are all kinds of POTWs. ALL kinds.
Monona
-----Original Message-----
From: neal**At_Symbol_Here**CHEMICAL-SAFETY.COM
To: DCHAS-L**At_Symbol_Here**Princeton.EDU
Sent: Fri, Jun 10, 2022 5:18 pm
Subject: Re: [DCHAS-L] [EXTERNAL] [DCHAS-L] Disposing of kanamycin
If I were in this situation, I would contact thee local POTW (sewer authority) and ask. If they say NO, nothing is lost. If they say YES, you win.
------------------------------------------------------------------------------------
Stay healthy and prosper
NEAL LANGERMAN, Ph.D.
ADVANCED CHEMICAL SAFETY, Inc. (Retired)
5340 Caminito Cachorro
SAN DIEGO CA 92105
+1 (619) 990-4908
From: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**Princeton.EDU> On Behalf Of Augspurger, Ashley
Sent: Friday, June 10, 2022 12:58 PM
To: DCHAS-L**At_Symbol_Here**Princeton.EDU
Subject: Re: [DCHAS-L] [EXTERNAL] [DCHAS-L] Disposing of kanamycin
Hi Jennifer,
I've recently done a lot of research into antibiotic disposal. There are some antibiotics that will breakdown in an autoclave, but most don't which is why they should be discarded as hazardous waste and incinerated. There really aren't any other effective options I've found.
Ashley
Ashley Augspurger, PhD, CIH, CSP
EHS&S Specialist
Chemical Hygiene Officer
Laboratory Biosafety Officer
Safe Science is Good Science
Corteva Agriscience TM
7000 NW 62nd Ave. PO Box 1000 | Johnston, IA 50131
515-535-6382 (w) | 515-350-8387 (c)
One of our researchers uses kanamycin in their antibiotic resistance studies. The total amount used over 10 weeks is about 100mg and would never exceed 200mg. They are working with microgram quantities on a weekly basis.
The NIH Drain Disposal guide suggests kanamycin should be treated as hazardous waste (collected and sent to disposal) Is anyone familiar with alternative disposal for kanamycin? Our concern is the very small amount of kanamycin in the large amount of water and bleach would have a drastic effect on our waste stream.
Is bleach sufficient to render the kanamycin appropriate for drain disposal? I have also seen suggestions that kanamycin be treated with acid to render it inactive and thus okay for drain disposal; but then wonder would neutralizing the acid (to make that appropriate for drain disposal) nullify the acid inactivation?
We do have access to an autoclave, but the NIH guide seems to suggest heat does not render kanamycin safe for the drain.
Your thoughts are appreciated,
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