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Subject: [DCHAS-L] CSB Releases Chemical Incident Data from Accidental Release Reporting Rule

Date: Jul 29, 2022 18:56 UTC

Author: Ralph Stuart <membership**At_Symbol_Here**DCHAS.ORG>

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Subject: Re: [DCHAS-L] [External] [DCHAS-L] Ethyl Acetate experience Q

Date: Jul 30, 2022 00:04 UTC

Author: Peairs, William <William.Peairs**At_Symbol_Here**CSHS.ORG>

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From: Ian Zastrow <ianzastrow**At_Symbol_Here**GMAIL.COM>

Subject: [DCHAS-L] Ethyl Acetate experience Q

Date: Jul 29, 2022 22:49 UTC

Reply-To: ACS Division of Chemical Health and Safety

In-Reply-To:  

Demystify: 

Good afternoon, I have a question for the group:
Does anyone have experience using Ethyl Acetate in large quantities?
I have run extraction using Ethyl acetate as a primary solvent and some actetylation. 4x 200L reactors. Ventilation in iso8.
Have not had any problems.

What are risks to lab employees with regards to possible inhalation exposure?
I have been asked to contribute as a consultant to a phytochemical extraction facility and there ventilation is c1d2...yet I would guess that is questionable.

Does Ethyl acetate present a major health risk to employees (55 gallon size batches) with likely vapor inhalation exposure?
EPA and SDS data sheets are a bit lacking and contradicting for me to hold a strong stance on this other than full iso8 and limit all exposure with best practices.
I would like to get some personal experience and anecdotal opinions.

Assuming full face respirators are used with organic vapor cartridges, would this not be safe?
Thank you for any input.





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