I would also point out that "effects" does not necessarily mean "deleterious effects," although it can include those.

-- PLZ

-----Original Message-----
From: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**Princeton.EDU> On Behalf Of Ralph Stuart
Sent: Friday, October 7, 2022 7:40 AM
To: DCHAS-L**At_Symbol_Here**Princeton.EDU
Subject: Re: [DCHAS-L] ACS EST: Rethinking Subthreshold Effects in Regulatory Chemical Risk Assessments

> >In my opinion, if you are demonstrating what some characterize as "subthreshold effects," you need to redefine the threshold.

I believe that is the point of the article.The variety of health impacts related to chemical exposures is so diverse that the concept of a “threshold value” is dubious at a practical level, although it may be necessary at the policy level.

- Ralph

Ralph Stuart, CIH, CCHO
ralph**At_Symbol_Here**rstuartcih.org

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