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Subject: Re: [DCHAS-L] Changes at C&EN

Date: Dec 20, 2022 18:47 UTC

Author: Monona Rossol <0000030664c37427-dmarc-request**At_Symbol_Here**LISTS.PRINCETON.EDU>

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Subject: Re: [DCHAS-L] Changes at C&EN

Date: Dec 20, 2022 19:09 UTC

Author: Ralph Stuart <ralph**At_Symbol_Here**RSTUARTCIH.ORG>

From: Ralph Stuart <ralph**At_Symbol_Here**RSTUARTCIH.ORG>

Subject: Re: [DCHAS-L] ChatGPT and Chemical Safety

Date: Dec 20, 2022 19:03 UTC

Reply-To: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**Princeton.EDU>

Message-ID: <A368760E-67DA-4ED1-9A4B-A0547BCB2593**At_Symbol_Here**rstuartcih.org>

In-Reply-To: <1494933528.2341916.1671555441033**At_Symbol_Here**mail.yahoo.com>

Demystify: 

> >Well, dang, the bot missed the most interesting thing about DMSO which is that it absorbs through the skin. Shortly after getting it on your skin you can taste it.

Yes, I don’t expect any artificial intelligence system to stand alone in developing professional advice. However, my hope is that the potential for a well trained chatbot is to help orient people to the general information available on a specific question. This information should form the basis for a more detailed discussion with someone with professional expertise in the field.

Interestingly, there are new features this week on the web site that
1) allow you to save and review previous questions and answers
and
2) ask for the response to be re-generated. These regenerated statements are not just editorial, but include new information sources. (examples below)

For example, I asked for the response to be regenerated on the DMSO question and the points you raise about it came up on the reruns of the question. My primary concern about the response overall is in the closing disclaimer statement to "you should consult a healthcare professional for advice”. I have had experience with many healthcare professionals who don’t have experience with providing advice about workplace chemical exposures. But that’s an ongoing challenge for most occupational health discussions...

- Ralph

Ralph Stuart, CIH, CCHO
ralph**At_Symbol_Here**rstuartcih.org
===
First response:
What are health concerns associated with DMSO?

Dimethyl sulfoxide (DMSO) is a colorless liquid that is sometimes used as a dietary supplement and as a topical treatment for pain and inflammation. It is also used in some industrial and laboratory settings.

DMSO can cause a number of side effects when it is used topically, including skin irritation, redness, and itching. It can also cause a garlic-like taste in the mouth when it is ingested.

There is some evidence to suggest that DMSO may be harmful when inhaled or ingested. Inhaling high concentrations of DMSO can cause respiratory irritation and lung damage, and ingesting large amounts of DMSO can cause gastrointestinal irritation and ulceration.

There is also some concern about the long-term safety of DMSO, as it has the potential to interact with certain medications and to interfere with the metabolism of some drugs.

It is important to use caution when using DMSO and to follow the instructions of a healthcare professional or the product label carefully. If you are concerned about the potential risks of using DMSO, you should consult a healthcare professional for advice.
===
Second response:
What are health concerns associated with DMSO?

Dimethyl sulfoxide (DMSO) is a chemical solvent that is sometimes used as a natural remedy for a variety of health conditions. However, there are some potential health concerns associated with the use of DMSO.

One concern is that DMSO can be absorbed through the skin and may have effects on the body when ingested. It is not clear what the long-term effects of using DMSO might be, and more research is needed to understand its safety and effectiveness.

DMSO can also cause skin irritation, redness, and blistering when applied to the skin. It can also cause eye irritation and other eye problems if it comes into contact with the eyes.

In addition, DMSO may interact with other medications that you are taking and may cause unwanted side effects. It is important to talk to a healthcare professional before using DMSO to understand the potential risks and benefits.

===
Where can I find information about the hazards of DMSO?

There are several sources of information about the hazards of DMSO. One source is the Material Safety Data Sheet (MSDS) for DMSO, which is a document that provides information about the chemical's physical and chemical properties, hazards, and safe handling and storage practices. MSDSs are usually available from the manufacturer or supplier of the chemical.

You can also find information about the hazards of DMSO in the scientific literature and on government websites. The National Institute for Occupational Safety and Health (NIOSH) and the Occupational Safety and Health Administration (OSHA) are both agencies within the U.S. Department of Labor that provide information about the hazards of chemicals, including DMSO.

In addition, the International Chemical Safety Cards (ICSCs) provided by the World Health Organization (WHO) and the European Chemicals Agency (ECHA) contain information about the hazards of DMSO and other chemicals. These resources can be accessed online and may be useful if you are looking for information about the hazards of DMSO.

===
Where can I find information about the hazards of DMSO?

There are several sources of information about the hazards of dimethyl sulfoxide (DMSO). Here are a few:
• The Occupational Safety and Health Administration (OSHA) has information about the hazards of DMSO in the workplace. This includes information about the potential health effects of DMSO and how to protect workers from these effects.
• The National Institute for Occupational Safety and Health (NIOSH) also has information about the hazards of DMSO in the workplace. This includes information about the potential health effects of DMSO and how to protect workers from these effects.
• The Environmental Protection Agency (EPA) has information about the environmental hazards of DMSO. This includes information about the potential effects of DMSO on the environment and how to protect the environment from these effects.
• The Agency for Toxic Substances and Disease Registry (ATSDR) has information about the health effects of DMSO. This includes information about the potential health effects of DMSO and how to protect yourself from these effects.

It is important to carefully read and understand the information provided by these and other reputable sources before using or handling DMSO. If you have any concerns or questions, you should consult a healthcare professional or a qualified toxicologist for advice.

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