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Subject: Re: [DCHAS-L] Phenolphthalein or Replacement?

Date: Nov 11, 2025 21:28 UTC

Author: Jeffrey Lewin <jclewin**At_Symbol_Here**MTU.EDU>

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Subject: Re: [DCHAS-L] Phenolphthalein or Replacement?

Date: Nov 12, 2025 16:26 UTC

Author: Info <info**At_Symbol_Here**ILPI.COM>

From: Pemberton, Drew (apemberton**At_Symbol_Here**uidaho.edu) <0000231dd2f469c4-dmarc-request**At_Symbol_Here**LISTS.PRINCETON.EDU>

Subject: Re: [DCHAS-L] Phenolphthalein or Replacement?

Date: Nov 11, 2025 22:13 UTC

Reply-To: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**Princeton.EDU>

Message-ID: <CY4PR04MB125563DE6C16902313063117A7CFA**At_Symbol_Here**CY4PR04MB1255.namprd04.prod.outlook.com>

In-Reply-To: <B1547748-6F51-4327-9161-C9E144D1F732**At_Symbol_Here**utdallas.edu>

Demystify: 

All,

 

Related question to phenolphthalein; my experience with it is that is it very commonly used as a pH indicator, particularly in general chemistry titration labs.

 

According to the SDS, phenolphthalein is considered a reproductive hazard and a carcinogen (category 2 for both). How do you handle this when it comes to classifying this as a PHS under OSHA’s 29 CFR 1910.1450(e)(3)(viii)? Do you switch to using something else, or is the exposure more concentration dependent? I’m starting to think about this as I’m working on a pregnancy in lab policy for my institution, and general chemistry tends to be where we see the highest volume of students who could potentially be or become pregnant.

 

Regards,

 

DREW PEMBERTON
Laboratory Safety Officer
Environmental Health and Safety
apemberton**At_Symbol_Here**uidaho.edu

Office: 208-885-5031

Mailing Address: 875 Perimeter Dr MS2030  |  Moscow ID 83844   |  United States

 

Physical Address:1108 W 6th St  |  Moscow ID 83844   |  United States

 

 

 

 

From: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**Princeton.EDU> On Behalf Of Leach, Patricia
Sent: Tuesday, November 11, 2025 9:12 AM
To: DCHAS-L**At_Symbol_Here**Princeton.EDU
Subject: Re: [DCHAS-L] Phenolphthalein or Replacement?

 

We dispose of it as hazardous waste. Patricia Leach Lab Manager Department of Chemistry & Biochemistry University of Texas at Dallas Cell: (469) 891-6426 On Nov 11, 2025, at 10:29 AM, Jack Reidy <jreidy2@stanford.edu> wrote:  Hi all,

We dispose of it as hazardous waste. 

 

Patricia Leach

Lab Manager

Department of Chemistry & Biochemistry

University of Texas at Dallas

Cell: (469) 891-6426



On Nov 11, 2025, at 10:29AM, Jack Reidy <jreidy2**At_Symbol_Here**stanford.edu> wrote:



Hi all,

 

I’m not sure what our labs currently use, but I remember that when they were shipping lab kits out during COVID, they used red cabbage as an indicator.


Sincerely,

 

Jack Reidy (he/him)

Research Safety Specialist & Chemical Hygiene Officer

Environmental Health & Safety

Stanford University

484 Oak Road, Stanford, CA, 94305

Tel: (650) 497-7614

 

I acknowledge that the land on which I live and work is the ancestral and unceded land of the Muwekma Ohlone Tribe. As an uninvited guest on these lands, I am a beneficiary of the ongoing displacement of the Ohlone people. I pay my respects to the Native peoples, past and present.

 

From: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**Princeton.EDU> On Behalf Of David EldrEdge
Sent: Monday, November 10, 2025 6:08 AM
To: DCHAS-L**At_Symbol_Here**Princeton.EDU
Subject: [DCHAS-L] Phenolphthalein or Replacement?

 

Our School's EHS responded to a question that was brought up about phenolphthalein:

 

"I verified this with the wastewater district, and they confirmed that it [phenolphthalein] cannot be disposed of down the drain. I want to be cautious here if we start discharging materials improperly, it could trigger a wastewater audit and potentially open Pandora’s box for the college."

 

What do you all do? Are you still using phenolphthalein or have you replaced phenolphthalein with something like bromthymol blue or something similar?  Do you get the same results or better? 

 

or...

 

Are you still using phenolphthalein, if so how do you deal with the waste? If collecting the waste, is it worth the cost of disposal? 

 

Warm regards,

 

David EldrEdge

Co-Owner

NALTIC Industrials, LLC

888.891.0077 Main

435.503.4972 Cell

435.767.7714 Google Voice & Text

435.654.2727 Fax

 

 

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