A safer butyl lithium quench: Slowly add the butyl lithium ( using a double tipped needle with nitrogen pressure) to crushed dry ice. The butyl group adds to CO2 and forms the lithium salt of pentanoic acid. The dry ice also keeps everything very cold. When adding butyl lithium to alcohol, butane is formed along with lots of heat. You are setting yourself up for a fire/explosion.
Previous post | Top of Page | Next post