Date: Tue, 5 Sep 2006 13:24:46 -0500
Reply-To: Amy Bullis <abullis**At_Symbol_Here**MSN.COM>
Sender: DCHAS-L Discussion List <DCHAS-L**At_Symbol_Here**LIST.UVM.EDU>
From: Amy Bullis <abullis**At_Symbol_Here**MSN.COM>
Subject: Re: Antineoplastic Drug Disposal
Comments: To: Michael Kleinman

I happen to be a Chemist in an Oncology Pharmacy, so I deal with this eve
ry day.  All hazardous drugs (which includes antineoplastics, some antibi
otics, endocrine disruptors, etc) need to be disposed of in your RCRA was
te.  Any animal bedding, excreta etc should be sterilized then also dispo
sed of in your RCRA waste.  We also dispose of our monoclonal antibodies 
as RCRA waste because although these drugs are supposed to be targeted, w
e now know that some of them have actions other than what was intended.  
Since we don't know what effect they may have on aquatic organisms, we er
r on the safe side and treat them as hazardous also.

Amy Bullis

----- Original Message -----
From: Michael Kleinman
Sent: Monday, September 04, 2006 23:52
To: DCHAS-L**At_Symbol_Here**LIST.UVM.EDU
Subject: Re: [DCHAS-L] Antineoplastic Drug Disposal

After sterilization the stuff can be treated as hazardous waste.

Mike Kleinman

-----Original Message-----
From: DCHAS-L Discussion List [mailto:DCHAS-L**At_Symbol_Here**LIST.UVM.EDU] On Behalf Of
Debra Decker
Sent: Friday, September 01, 2006 12:32 PM
To: DCHAS-L**At_Symbol_Here**LIST.UVM.EDU
Subject: [DCHAS-L] Antineoplastic Drug Disposal

Apologies for the cross-posting.  I know we've probably covered this
before, but I just can't put my hands on the information this morning

A researcher is working with 3 antineoplastic drugs that are also
considered hazardous materials/hazardous waste.  Naturally, questions
arise about disposal of clinical lab trash, animal and animal bits
contaminated with these materials, animal bedding, etc.

The 3 drugs are cytarabine, methotrexate, vincristine.

Is disposal as hazardous waste appropriate or necessary?  What about the
medical waste potential?  The haz waste folks won't take medical waste -
the med waste folks won't take haz waste.


Debbie Decker
EH&S UCDavis
FAX (530)752-4527
Co-Conspirator to Make the World A  
Better Place -- Visit and join the conspiracy

Birkett's hypothesis: "Any chemical reaction  
that proceeds smoothly under normal conditions,  
can proceed violently in the presence of an idiot."

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