We have b een working on this issue for the past year also. < /p>
We changed the IACUC chemical hazard form that investigators fi ll out for animal protocols to include:
· Marking substances as carcinogens, toxics, reprod uctive hazards, cytotoxic/antineoplastic agents, investigational drugs with limited safety data, and/or nanoparticles or nanoparticle formulation.
· ;   ; Based on what the y mark on the form our animal husbandry staff now designate certain cages a s chemical hazards, post the door and treat the waste (cages/bedding/water bottles/carcasses) differently.
· Split the risk assessment section up into “M aterials Handling/Administration” and “Cage Changing” so that both researchers and husbandry staff are addressed p>
We have also started writing SOPS for specific hazardous chemica ls used in animals that address issues related to both researchers and husb andry staff.
Chemical Hygiene Officer
Environment, Health and Safety
s Drive Extension
University of North Ca rolina at Chapel Hill
Chapel Hill, NC 27599-1650
(919) 962-0227 FAX
We are working this out as we s peak. Very timely question.
From a chemical h ygiene standpoint I want the researchers, in their animal use protocols, to provide hazard info and/or LD50 info for all chemicals used in protocols t o assess the chemical handling requirements for those chemicals under the l ab standard.
If the fall into OSHAs “p articularly hazardous substances” (carcinogens, reproductive toxins, or acutely toxic chemicals) then they should be handled in a containment (i f decanted) or a closed system (syringe or gavage).< p class="MsoNormal">
We also look for compliance with the use of controlled substances a t that time and any issues for waste handling of bedding or animal carcasse s for the animal care personnel.
Christopher E. Kohler
Certified Chemical Hygiene Officer
Laboratory Safety Manager
Office of Environmental, Health, and Safety Management
1514 East Third Street
Bloomington, IN 47405
I am try ing to get information from peer institutions about how they manage worker safety in regard to exposure to chemicals administered to lab animals.  ; Does anyone have any expertise in this issue?
Thank you-< /p>