Date: Thu, 9 Dec 2010 14:39:25 -0500
Reply-To: DCHAS-L Discussion List <DCHAS-L**At_Symbol_Here**LIST.UVM.EDU>
Sender: DCHAS-L Discussion List <DCHAS-L**At_Symbol_Here**LIST.UVM.EDU>
From: "Brennan, Catherine (Environment Health & Safety)"

Subject: Re: Chemical Safety and Lab Animals
In-Reply-To: <E752169501F682479C7114A8D5669178075AC866**At_Symbol_Here**>

We have b een working on this issue for the past year also.  < /p>

We changed the IACUC chemical hazard form that investigators fi ll out for animal protocols to include:

·         Marking substances as carcinogens, toxics, reprod uctive hazards, cytotoxic/antineoplastic agents, investigational drugs with limited safety data, and/or nanoparticles or nanoparticle formulation.

· ;      ;    Based on what the y mark on the form our animal husbandry staff now designate certain cages a s chemical hazards, post the door and treat the waste (cages/bedding/water bottles/carcasses) differently. 

·         Split the risk assessment section up into “M aterials Handling/Administration” and “Cage Changing” so that both researchers and husbandry staff are addressed

We have also started writing SOPS for specific hazardous chemica ls used in animals that address issues related to both researchers and husb andry staff.



Catherine R. Brennan

Chemical Hygiene Officer


Environment, Health and Safety

1120 Este s Drive Extension

University of North Ca rolina at Chapel Hill

Chapel Hill, NC  27599-1650

(919) 843-5331

(919) 962-0227 FAX

From: DCHAS-L Discussion List [mailto:DCHAS-L**At_Symbol_Here**] On Behalf Of Kohler, Christopher E
Sent: Thursday, December 09, 2010 1:25 PM
To: DCHAS-L**At_Symbol_Here**LIST.UVM.EDU
Subject: Re: [DCHAS-L] Chemical Safety and Lab Animals


We are working this out as we s peak. Very timely question.

From a chemical h ygiene standpoint I want the researchers, in their animal use protocols, to provide hazard info and/or LD50 info for all chemicals used in protocols t o assess the chemical handling requirements for those chemicals under the l ab standard.

 < /o:p>

If the fall into OSHAs “p articularly hazardous substances” (carcinogens, reproductive toxins, or acutely toxic chemicals) then they should be handled in a containment (i f decanted) or a closed system (syringe or gavage).

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We also look for compliance with the use of controlled substances a t that time and any issues for waste handling of bedding or animal carcasse s for the animal care personnel.


Christopher E. Kohler

Certified Chemical Hygiene Officer

Laboratory Safety Manager

Indiana University

Office of Environmental, Health, and Safety Management

1514 East Third Street

Bloomington, IN 47405

(812) 855-6311


From: DCHAS-L Discussion List [mailto:DCHAS-L**At_Symbol_Here**L IST.UVM.EDU] On Behalf Of Johnson, Amy Carr
Sent: Thursday , December 09, 2010 12:21 PM
To: DCHAS-L**At_Symbol_Here**LIST.UVM.EDU
Subje ct: [DCHAS-L] Chemical Safety and Lab Animals


I am try ing to get information from peer institutions about how they manage worker safety in regard to exposure to chemicals administered to lab animals.  ; Does anyone have any expertise in this issue?

Thank you-< /p>

Amy Johnson

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