From: NEAL LANGERMAN <neal**At_Symbol_Here**>
Subject: Re: [DCHAS-L] Nitration, safe work with nitric acid
Date: Thu, 2 Apr 2015 13:48:10 -0700
Reply-To: DCHAS-L <DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU>
Message-ID: 030701d06d86$556cbfe0$00463fa0$**At_Symbol_Here**
In-Reply-To <8CDFD30A507F9B4DBFE1486FA3AFCF6631EFD171**At_Symbol_Here**MAILSRV.DELMAR.LOCAL>

There is a huge body of literature on making nitrating acid solutions and for safely carrying out nitrations. Bretherick is certainly the starting place, but a good search on Science Direct and SciFinder is called for. Then, before you do bench work, develop an SOP and go over it in detail with peers and SMEs.






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From: DCHAS-L Discussion List [mailto:dchas-l**At_Symbol_Here**MED.CORNELL.EDU] On Behalf Of Nadejda Spassova
Sent: Thursday, April 02, 2015 1:12 PM
Subject: [DCHAS-L] Nitration, safe work with nitric acid



Hi all,


Recently I start working on a project involving nitration with nitric acid, does anyone has an experience with this kind of reaction ? Also we are mixing nitric acid and acetic acid and then adding the compound to be nitrate, how dangerous is the mixing of the two acids I read that they are incompatible ?


Kind regards,







Nadejda Spassova, Ph.D

Research Scientist II, R&D                                                                 T 514.366.7950ext. 270


9321, Airlie Street, LaSalle, Quebec, Canada H8R 2B2              

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