I've seen it ever since I started watching the early UN Purple book editions which was in the late 1990s I think.  I'd never seen it before then. 

 

But you have the right definition.  In the US, we seem to only be concerned about Cancer, repro and developmental, and neurotoxicity in our regulatory definitions of chronic toxicity (see Prop 65 for a state rule, and 16 CFR 1500.135 for the CPSC Federal Hazardous Substances Act  definition).   But some chemicals can cause long term damage to other organs like the kidneys, liver, etc.   What STOT means is chronic testing should be done to see what damage occurs over time to all organ systems.

 

 

 

 

 

-----Original Message-----
From: Kennedy, Sheila <s1kennedy**At_Symbol_Here**UCSD.EDU>
To: DCHAS-L <DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU>
Sent: Tue, Apr 14, 2015 1:11 pm
Subject: [DCHAS-L] SDS acronym | STOT