From: "CHANDRA, Tilak" <tchandra**At_Symbol_Here**FPM.WISC.EDU>
Subject: Re: [DCHAS-L] Rotovaps and ventilation
Date: Wed, 23 Sep 2015 14:27:11 +0000
Reply-To: DCHAS-L <DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU>
Message-ID: AC64846C6B11EE4F97DEDF3ED857D65C81AB86EB**At_Symbol_Here**

If azides/peroxide formers are regularly manipulated for the peptide and carbohydrates syntheses in a lab, a rotavapor inside a chemical fume hood will provide additional safety. Also, a roptavapor inside a chemical fume hood will reduce the odor problem during thiol chemical manipulations. For regular chemical manipulations, rotavapor on a benchtop corner serves the purpose very well in syntheses labs.





Tilak Chandra, Ph.D.

Chemical Safety Specialist






From: DCHAS-L Discussion List [mailto:dchas-l**At_Symbol_Here**] On Behalf Of ILPI Support
Sent: Tuesday, September 22, 2015 11:22 AM
Subject: Re: [DCHAS-L] Rotovaps and ventilation


Unless you're in a magical world where hood space is more widely available than PAC money, I'd have to say that safety/ventilation etc. is way down the list for most PI's.  In many all of the labs I've worked in, hood space is too valuable (i.e.. scarce) to take up with a rotovap, and a rotavap setup is so bulky and difficult to move it would impractical to move it into a hood if you had something really nasty.  In that case, we'd instead remove the solvent with a vacuum/Schlenk line that is already in the hood.


That said, one should always set up proper traps, pumps, venting and safety shields for rotavaps used on an open bench top.  I assume various places have SOP's for that. 


Rob Toreki



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On Sep 22, 2015, at 9:16 AM, "Stuart, Ralph" <Ralph.Stuart**At_Symbol_Here**> wrote:

Random question for the morning:
What factors determine whether a rotovap should be used in a hood or not?

Thanks for any feedback on this.

- Ralph

Ralph Stuart, CIH, CCHO
Chemical Hygiene Officer
Keene State College



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