If azides/peroxide formers are regularly manipulated for the peptide and carbohydrates syntheses in a lab, a rotavapor inside a chemical fume hood will provide additional safety. Also, a roptavapor inside a chemical fume hood will reduce the odor problem during thiol chemical manipulations. For regular chemical manipulations, rotavapor on a benchtop corner serves the purpose very well in syntheses labs.
Tilak Chandra, Ph.D.
Chemical Safety Specialist
Unless you're in a magical world where hood space is more widely available than PAC money, I'd have to say that safety/ventilation etc. is way down the list for most PI's. In
many all of the labs I've worked in, hood space is too valuable (i.e.. scarce) to take up with a rotovap, and a rotavap setup is so bulky and difficult to move it would impractical to move it into a hood if you had something really nasty. In that case,
we'd instead remove the solvent with a vacuum/Schlenk line that is already in the hood.
That said, one should always set up proper traps, pumps, venting and safety shields for rotavaps used on an open bench top. I assume various places have SOP's for that.
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On Sep 22, 2015, at 9:16 AM, "Stuart, Ralph" <Ralph.Stuart**At_Symbol_Here**keene.edu> wrote:
Random question for the morning:
What factors determine whether a rotovap should be used in a hood or not?
Thanks for any feedback on this.
Ralph Stuart, CIH, CCHO
Chemical Hygiene Officer
Keene State College
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