From: Kimberly Bush <kimibush**At_Symbol_Here**ehrs.upenn.edu>
Subject: Re: [DCHAS-L] Storing Pyrophoric/Water-Reactive Reagents at low temperature
Date: Wed, 18 Nov 2015 15:34:16 +0000
Reply-To: DCHAS-L <DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU>
Message-ID: B4B6538F0A43D942A1222900CC58119AF0910C4F**At_Symbol_Here**exch-mbx03.exchange.upenn.edu
In-Reply-To


I would like to add that some protocols recommend allowing containers of refrigerated, water-sensitive reagents to warm to room temperature prior to opening.  This will reduce the amount of condensation that forms.  We would hope that the introduction of moisture to the inside of a septa-sealed bottle would be minimal-to-impossible, but it’s worth considering when handling materials that can safely warm to room temperature prior to use.  (Obviously, heat should not be applied to the container to facilitate warming)

 

Often this room-temp opening advice is given for bottles that are not septa-sealed, and contain moisture-sensitive or very hydroscopic chemicals, whether or not there is any safety implications of the moisture being introduced to the container.

 

Kimi Bush

Lab Safety Specialist

Environmental Health and Radiation Safety

University of Pennsylvania

3160 Chestnut St., Suite 400

Philadelphia, PA 19104-6287

Office: 215-746-6549

Voice/cell/text:  215-651-0557

fax: 215-898-0140

 

From: DCHAS-L Discussion List [mailto:dchas-l**At_Symbol_Here**med.cornell.edu] On Behalf Of TILAK CHANDRA
Sent: Wednesday, November 18, 2015 9:54 AM
To: DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU
Subject: Re: [DCHAS-L] Storing Pyrophoric/Water-Reactive Reagents at low temperature

 

Hi Jenny:

 

It is ok to store water sensitive reagents (pyrophorics too) inside an explosion proof refrigerator. Make sure your reagent bottle is under nitrogen atmosphere and cap is closed properly. You may also apply a Teflon tape around the cap and use a secondary containment inside refrigerators main compartment to avoid the sliding of the reagent bottle.

 

Good luck.

 

Tilak

 

From: DCHAS-L Discussion List [mailto:dchas-l**At_Symbol_Here**med.cornell.edu] On Behalf Of Fu, Zhen
Sent: Tuesday, November 17, 2015 4:01 PM
To: DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU
Subject: [DCHAS-L] Storing Pyrophoric/Water-Reactive Reagents at low temperature

 

Hi All,

 

I read some Protocols for Safe Use of Pyrophoric/Water-Reactive Reagents mentioned “When refrigeration of materials is required, materials must be stored in an approved explosion-proof refrigerator/freezer.” As we all know, even the explosion-proof refrigerator/freezer cannot provide dry environment.

 

Can you share your experience on storing pyrophoric, flammable, and water-sensitive substances such as tBuLi solution in pentanes at low temperature? Great Thanks!

 

Jenny

 

Best Regards,

 

Zhen (Jenny) Fu, Ph.D., Sr. Safety Specialist, Environmental Health & Life Safety

Administration & Finance / Dept. of Public Safety

University of Houston

713-743-8723

zfu2**At_Symbol_Here**uh.edu

Previous post   |  Top of Page   |   Next post



The content of this page reflects the personal opinion(s) of the author(s) only, not the American Chemical Society, ILPI, Safety Emporium, or any other party. Use of any information on this page is at the reader's own risk. Unauthorized reproduction of these materials is prohibited. Send questions/comments about the archive to secretary@dchas.org.
The maintenance and hosting of the DCHAS-L archive is provided through the generous support of Safety Emporium.