From: TILAK CHANDRA <tilak.chandra**At_Symbol_Here**WISC.EDU>
Subject: Re: [DCHAS-L] safety of nucleophilic fluorination reagents
Date: Tue, 27 Feb 2018 01:02:07 +0000
Reply-To: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**PRINCETON.EDU>
Message-ID: DM5PR06MB3195770D43CA99EC1E19321A88C00**At_Symbol_Here**

Hi Kristi:


There is a low probability of generating HF as a side product during nucleophilic fluorination. By the way which method researcher is using for forming the C-F bond? There are various methods available in the literature for such fluorination.


Good luck.



From: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**PRINCETON.EDU> on behalf of Kristi Ohr <kohr**At_Symbol_Here**UMASS.EDU>
Sent: Monday, February 26, 2018 5:06:04 PM
Subject: [DCHAS-L] safety of nucleophilic fluorination reagents

Is anyone else treating nucleophilic fluorination reagents in the same way as HF in terms of precautions and emergency response?  I'm not finding any data on the subject aside from recommendations to have calcium gluconate on hand in SDSs.






Kristi Ohr, Ph.D.
Chemical Safety Services Manager

Environmental Health and Safety
UMass Amherst
40 Campus Center Way
Draper Hall
Amherst, MA 01003
Office: 413-545-5117

Cell: 413-800-4408



--- For more information about the DCHAS-L e-mail list, contact the Divisional membership chair at membership**At_Symbol_Here** Follow us on Twitter **At_Symbol_Here**acsdchas

Previous post   |  Top of Page   |   Next post

The content of this page reflects the personal opinion(s) of the author(s) only, not the American Chemical Society, ILPI, Safety Emporium, or any other party. Use of any information on this page is at the reader's own risk. Unauthorized reproduction of these materials is prohibited. Send questions/comments about the archive to
The maintenance and hosting of the DCHAS-L archive is provided through the generous support of Safety Emporium.