From: Richard Rosera <richardrosera**At_Symbol_Here**GMAIL.COM>
Subject: Re: [DCHAS-L] SDS - Section 2 Hazards for sulfuric acid
Date: Mon, 24 Sep 2018 17:22:03 -0600
Reply-To: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**PRINCETON.EDU>
Message-ID: 20B516BB-9B1D-4859-AF27-E0170AD7EC85**At_Symbol_Here**
In-Reply-To <002501d45447$1b2d45b0$5187d110$**At_Symbol_Here**>



Try these links, they are mostly classic papers from process safety literature.  These papers primarily focus on thermal runaway and pressure generation that can lead to catastrophic equipment failure.  They don’t address issues of occupational exposure to chemicals.


Recommended Literature for Process Safety


Note:  Recommend documents 2, 3, and 5 as introductory literature


Thermal Risk Evaluation


1.       Chemical Rxn Engineering Safety Gygax 1988 -


2.       Townsend, Thermal hazard evaluation by an accelerating rate calorimeter;


3.       Stoessel review in OPRD_1997:


4.       Stoessel Planning protection measures against runaway reactions using criticality classes 2009:


5.       Selection of the Proper Calorimetric Test Strategy in Reactive Chemicals Hazard Evaluation, Frurip (Dow Chemical) - OPRD 2008 -



Pressure Relief Evaluation


6.       Fauske Monogram 1984 Generalized Vent Sizing Monogram for Runaway Chemical Reactions:


7.       Comparison of pressure-relief calculation methods;  - list of original references for models and data


Training Sources (2017)

A.       AIChE DIERS training


B.       CCPS;


C.       Dekra Course Calendar:


D.    Fauske Training


E.     Mettler Toledo Training course list (live & web)


F.     Iomosaic Training -



Best, chuck

From: ACS Division of Chemical Health and Safety [mailto:DCHAS-L@PRINCETON.EDU] On Behalf Of Jeffrey R. Cogswell
Sent: Tuesday, September 25, 2018 11:04 AM
Subject: [DCHAS-L] Papers on risks of scaling up reactions


EXTERNAL EMAIL – Use caution with any links or file attachments.


I’m currently working on a safety talk about RAMP and decided to include a section on “RAMPing up Reactions”

It was discussed at ACS that scaling up reactions is a under-stated danger in many chemistry laboratories.


Does anyone have any suggestion for articles that talks about or quantifies the risks of increasing the yield in chemical reactions?


For example: I found very informative and it would be great to find more sources.




Jeffrey R. Cogswell, Ph.D.

Chemical Inventory and Laboratory Resource Center Technician, EHS

37 Dewey Field Road, HB 6216

Hanover, New Hampshire 03755


--- For more information about the DCHAS-L e-mail list, contact the Divisional membership chair at Follow us on Twitter @acsdchas

Notice:  This e-mail message, together with any attachments, contains
information of Merck & Co., Inc. (2000 Galloping Hill Road, Kenilworth,
New Jersey, USA 07033), and/or its affiliates Direct contact information
for affiliates is available at that may be confidential,
proprietary copyrighted and/or legally privileged. It is intended solely
for the use of the individual or entity named on this message. If you are
not the intended recipient, and have received this message in error,
please notify us immediately by reply e-mail and then delete it from
your system.

--- For more information about the DCHAS-L e-mail list, contact the Divisional membership chair at Follow us on Twitter @acsdchas

Previous post   |  Top of Page   |   Next post

The content of this page reflects the personal opinion(s) of the author(s) only, not the American Chemical Society, ILPI, Safety Emporium, or any other party. Use of any information on this page is at the reader's own risk. Unauthorized reproduction of these materials is prohibited. Send questions/comments about the archive to
The maintenance and hosting of the DCHAS-L archive is provided through the generous support of Safety Emporium.