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Ellen, 
After the incident at the 
Georgia Sperm Bank, our PD asked us to assess any spaces where a possible deficiency may occur.   We basically made some assumptions involving complete dead air (we have had a number of campus-wide power outages), calculated the volume of the laboratory
 (or other space), and then the size of the Dewar.  If the calculations showed that a 120 or 160L Dewar could displace enough oxygen to result in a low oxygen atmosphere, we installed local monitoring.   This included the NMR facility, a few labs using Dewars
 to act as a nitrogen gas source (we do not have house nitrogen), various storage rooms, and, last but not least - the room that houses SMU Athletics' cryotherapy unit.
Frankly, as alluded to, much of this is overkill.  We have had storage rooms drop down to about 19.4% when Dewars are venting as part of their pressure relief systems.  We recently had an NMR quench (that is a whole other story and involves
 a compressed air cylinder transported too close to the magnet).   Even then, during quenching, the oxygen in the NMR room never dropped below about 20%.  
Regards,
 
Brandon S. Chance, MS, CCHO
Director of Environmental Health and Safety
Southern Methodist University 
From: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**Princeton.EDU> on behalf of "Ellen M. Sweet" <ems325**At_Symbol_Here**CORNELL.EDU>
Reply-To: ACS Division of Chemical Health and Safety <DCHAS-L**At_Symbol_Here**Princeton.EDU>
Date: Wednesday, June 2, 2021 at 12:56 PM
To: "DCHAS-L**At_Symbol_Here**Princeton.EDU" <DCHAS-L**At_Symbol_Here**Princeton.EDU>
Subject: [DCHAS-L] benchmarking O2 monitoring with cryogen use
[EXTERNAL SENDER]
Hi everyone,
�Just doing some benchmarking. My question is what does your institution's assessment look like in order to determine when oxygen deficiency monitoring is needed for a proposal to use a cryogen liquid in a lab?
 
I look forward to hearing responses. 
Thanks, Ellen
 
Ellen Sweet
Laboratory Ventilation Specialist
Department of Environmental Health and Safety, Cornell University
American Chemical Society, Division of Chemical Health and Safety
315-730-8896
 
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