Date: Sun, 14 Mar 2010 09:46:11 -0500
Reply-To: DCHAS-L Discussion List <DCHAS-L**At_Symbol_Here**LIST.UVM.EDU>
Sender: DCHAS-L Discussion List <DCHAS-L**At_Symbol_Here**LIST.UVM.EDU>
From: "Nail, John" <jnail**At_Symbol_Here**OKCU.EDU>
Subject: Re: Inactivation of Meta chloro peroxybenzoic acid
In-Reply-To: <48A020E1942E024DB0F2A6B68A1312440788CB6911**At_Symbol_Here**>

Peroxyacids (RCO3H) are strong oxidizers; basically, they react by 'donatin
g' oxygen atoms to reducing agents

RCO3H + reducing agent --> RCO2H (a carboxylic acid) + Reducing agent + an 
O atom; further chemistry may occur with the oxidized reducing agent.

Any decent reducing agent will work; one advantage of using Fe+2 ions, such
 as in ferrous ammonium sulfate, is that the Fe+2 will be oxidized to Fe+3;
 this should give a color change which can be used to confirm that the reac
tion occurred.

To answer the question, there may not be a 'preferred method'; there are do
zens of reagents that should work.

-----Original Message-----
From: DCHAS-L Discussion List [mailto:DCHAS-L**At_Symbol_Here**LIST.UVM.EDU] On Behalf Of De
bbie M. Decker
Sent: Friday, March 12, 2010 5:57 PM
To: DCHAS-L**At_Symbol_Here**LIST.UVM.EDU
Subject: [DCHAS-L] FW: Inactivation of Meta chloro peroxybenzoic acid

Hey all you chemists out there!  I don't quite know where to begin to give 
my colleague, Dexter, advice.


-----Original Message-----
From: Dexter

We are using MCPBA to make some epoxides.  I need to purify the MCPBA 
before I use it and the wash and crystalization process leaves a 
significant anoumt in solution.  Usually dichloromethane. I will 
obviuosly discard this solution as toxic waste but I want to deactivate 
the MCPBA that remains.  I have read you can use NaI , ferrous ions, 
potassium hydroxide, sodium thiosulfate, etc.  What in your knowledge is 
the preferred method.  Thanks.   Dexter

Debbie M. Decker, Campus Chemical Safety Officer
Environmental Health and Safety
University of California, Davis
1 Shields Ave.
Davis, CA=A0 95616
(530)754-7964/(530)752-4527 (FAX)
Co-Conspirator to Make the World A 
Better Place -- Visit and join the conspiracy

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