From: Nadejda Spassova <nspassova**At_Symbol_Here**DELMARCHEM.COM>
Subject: [DCHAS-L] Clarification on : working with a high potency compound
Date: Tue, 11 Feb 2014 14:32:57 +0000
Reply-To: DCHAS-L <DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU>
Message-ID: 8CDFD30A507F9B4DBFE1486FA3AFCF660A980C**At_Symbol_Here**MAILSRV.DELMAR.LOCAL

Hi everybody,


Here is the clarification regarding my question : ‘’Working with a high potent compound’’


I am working in a pharmaceutical company and what I mean by high potency is very, very active compound (in that case active pharmaceutical ingredient = API) in the human body for the intended pharmacological effect. This generic drug that we will work on in the near future has a daily dosage of only 20 =B5g per day (for that reason I guess it was classified as high potent drug) compare to a low potent drug e.g. 20g per day.

On the other side the LD 50 (mouse) of this compound is 200mg per kg, so it is not very toxic.


Sorry about this misunderstanding and thanks to all of you for the efforts trying to answer my not clear enough question,







Nadejda Spassova, Ph.D

Research Scientist II, R&D                                                                 T 514.366.7950ext. 270


9321, Airlie Street, LaSalle, Quebec, Canada H8R 2B2              

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