From: "Wawzyniecki Jr, Stefan" <stefan.w**At_Symbol_Here**UCONN.EDU>
Subject: [DCHAS-L] N-100's for nanoparticle formulations.
Date: Mon, 19 Jan 2015 21:09:30 +0000
Reply-To: DCHAS-L <DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU>
Message-ID: 877A5F1406F1C9408F8D6DA88C8492852BB7C55F**At_Symbol_Here**


Much research is being conducted recently using nanoparticle formulations of chemotherapeutics as well as pain relief meds.  NIOSH and the Navy Public Health center have described the use of N 100’s as respiratory protection when working  with nanoparticles, and formulations.


My question is-


When evaluating animal research protocols involving formulations on the nanoscale such as chemotherapeutics, is anyone requiring N 100’s when the task isinjecting the medication, as opposed to actually formulating it?  One argument I hear from researchers is that their primary concern is autoinjection, which is why they have no problem with wearing gloves, but they would rather not  wear a respirator. 


Anyone involved in such risk assessment?


-Stefan Wawzyniecki, CIH, CHMM

University of Connecticut

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