From: Alan Hall <ahalltoxic**At_Symbol_Here**GMAIL.COM>
Subject: Re: [DCHAS-L] Assessing and predicting the health hazards of newly synthesized compounds for the development of SDSs.
Date: Mon, 12 Oct 2015 15:55:36 -0500
Reply-To: DCHAS-L <DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU>
Message-ID: CAHFAP+62SSWK0qij1aBXxNs0UB8FJVy6Y+8YTCL8Cw=jvjzTXQ**At_Symbol_Here**
In-Reply-To <71E50DF480EFA64BA856FD3CB7B11BE1ECCEFA08**At_Symbol_Here**>

There is a program developed by, if memory serves, ORISE and Oak Ridge Associated Universities that may address some of thjese concerns.

Alan H. Hall, M.D.
Medical Toxicologist

On Mon, Oct 12, 2015 at 9:58 AM, Rupkey, Steve <srupkey**At_Symbol_Here**> wrote:


What do others do to assess, predict and assign an OSHA 2012 health hazard classification to a newly synthesize compound develop by your home institution when you are required to develop a SDS?

I'm not so concerned about assessing the hazards of mixtures of known chemicals but concerned more about new compounds, where the new compound has no history of a health hazard evaluation and where using the precursor chemicals is not as reliable predictor of its health hazards/toxicity.

Does anyone use a toxicologist to review the chemical structure of the new compound to predict and present their "best judgment" regarding the health hazard classifications?


Steve Rupkey, CIH

Argonne National Laboratory


Previous post   |  Top of Page   |   Next post

The content of this page reflects the personal opinion(s) of the author(s) only, not the American Chemical Society, ILPI, Safety Emporium, or any other party. Use of any information on this page is at the reader's own risk. Unauthorized reproduction of these materials is prohibited. Send questions/comments about the archive to
The maintenance and hosting of the DCHAS-L archive is provided through the generous support of Safety Emporium.