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From: Louis DiBerardinis <loudib**At_Symbol_Here**MIT.EDU>
Subject: Re: [DCHAS-L] Assessing and predicting the health hazards of newly synthesized compounds for the development of SDSs.
Date: Oct 13, 2015 11:33 UTC
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DCHAS-L
In-Reply-To:
It has only happened a couple of times but in each case we hired a toxicologist ( retired from Polaroid who did this for them ).
Lou
From: DCHAS-L Discussion List [mailto:dchas-l**At_Symbol_Here**med.cornell.edu]
On Behalf Of Rupkey, Steve
Sent: Monday, October 12, 2015 10:59 AM
To: DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU
Subject: [DCHAS-L] Assessing and predicting the health hazards of newly synthesized compounds for the development of SDSs.
Greetings:
What do others do to assess, predict and assign an OSHA 2012 health hazard classification to a newly synthesize compound develop by your
home institution when you are required to develop a SDS?
I'm not so concerned about assessing the hazards of mixtures of known chemicals but concerned more about new compounds, where the new
compound has no history of a health hazard evaluation and where using the precursor chemicals is not as reliable predictor of its health hazards/toxicity.
Does anyone use a toxicologist to review the chemical structure of the new compound to predict and present their "best judgment" regarding
the health hazard classifications?
Sincerely,
Steve Rupkey, CIH
Argonne National Laboratory