From: J. Steven Bonnell <jsbonnell**At_Symbol_Here**CINCI.RR.COM>
Subject: Re: [DCHAS-L] Peroxide Formers Question
Date: Tue, 16 Aug 2016 17:53:37 -0400
Reply-To: DCHAS-L <DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU>
I have had little experience with stabilized peroxidizables. Those stabilizers throw funny spikes on HPLC. That notwithstanding, it would be my opinion that you would be best served by making a clear distinction between your stabilized and non-stabilized inventory so you can reliably expire off the materials in accordance with the manufacturers' recommendations. For the non-stabilized, check your expirations against those recommended by Lawrence Livermore Labs and adopt the more conservative.
Begin the expiration countdown for non-stabilized from the date of receipt into inventory or be prepared to periodically check aliquots on peroxide test strips. Be aware that standard peroxide strips are not sensitive to super-peroxides which can be even more dangerously unstable. For stabilized, that might be unnecessary testing if you are able to establish standard storage and handling strategies and spot test to validate.
We're in discussion with a research group who uses quite a number of materials flagged by our inventory system as being peroxide formers. Their claim is that certain of their materials will be unlikely to form peroxides because there are
other chemicals mixed in with things life THF and ether (for example, methylmagnesium bromide in THF). My thought is that their logic is sound, but I wanted to push the question to a broader group to see if there is a consensus out there.
Karalyn (Karen) Humphrey,
Laboratory Safety Program Manager
& Radiation Safety Officer
Department of Environmental, Health & Safety
Office: Draper 244.10
"- our job in safety is to make the task happen, SAFELY; not to interfere with the work=E2=80=A6" Neal Langerman
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