I can't believe people still think these are "unintended" consequences. The chemicals are in the same class. All the bisphenols can probably do some endocrine disrupting.
BPA-FREE WATER BOTTLES MAY CONTAIN ANOTHER HARMFUL CHEMICAL
Tags: us_MO, public, discovery, environmental, other_chemical
Talk about unintended consequences. A compound called BPA is being phased out of plastic packaging due to fears it may disrupt our hormones - but a replacement for it may be just as harmful.
BPA, or bisphenol A, is often found in disposable water bottles and babies' milk bottles and cups. Small amounts can dissolve into the food and drink inside these containers.
This is a concern because a host of studies have shown that BPA can mimic the actions of oestrogen, binding to the same receptor in the body. Oestrogen is normally involved in breast development, regulating periods and maintaining pregnancies. Animals exposed to BPA develop abnormal reproductive systems, but it is unclear if people are exposed to high enough doses to be affected.
Due to public pressure - and bans in a few countries - many manufacturers have started replacing BPA. One substitute, fluorene-9-bisphenol, or BHPF, is already widely used in a variety of materials.
But Jianying Hu of Peking University in Beijing and her team have found that BHPF also binds to the body's oestrogen receptors. Unlike BPA, it does this without stimulating them, instead blocking their normal activity.. In tests on female mice, BHPF caused the animals to have smaller wombs and smaller pups than controls, and in some cases miscarriages.
If BHPF binds to the same receptor in humans, it has the potential to cause fertility problems. "That's pretty scary," says Frederick vom Saal of the University of Missouri.
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