Safety Emporium for all your lab and safety needs

Nausea

Glossary Index

Neoplasm

MSDS Topics	Free Sites	FAQ's	Regulations	Glossary	Software	Suppliers
	Books	Forum	Poll	Fun stuff	Quiz	Store
Understand your MSDS with the MS-Demystifier				Search ALL our MSDS info

Necrosis

Definition

• Necrosis is the death of cells or tissue due to disease, injury, exposure to chemical agents, radiation etc.

Additional Info

Necrotic tissue can be found anywhere in the body, but is generally a localized phenomenon. When extremely large areas of tissue are involved, the condition is generally called gangrene.

Most acids produce coagulation necrosis when they contact bodily tissue, a process that produces an insoluble mass that limits the penetration of the acid and limits the damage. Most bases (as well as hydrofluoric acid) cause liquefaction necrosis which turns the affected tissue to a liquid that does not stop the penetration. Therefore while getting either on your skin or eyes is dangerous, exposure to bases can cause more damage than acids, particularly if not promptly treated.

MSDS Relevance Necrosis usually appears on an MSDS as a delayed or immediate symptom of exposure, usually through eye or skin contact. Corrosive materials may cause painful chemical burns and necrosis of the skin or eyes. Always wear proper personal protective equipment (PPE) such as gloves and goggles when dealing with such materials. See the entry on eye washes for special considerations/cautions when working with bases. Further Reading Radiation Necrosis and Burns, Chemical are chock full of info on the topics and are geared towards emergency room physicians. Acute Tubular Necrosis (ATN) by the Merck Manual. Questions and Answers about Osteonecrosis (Avascular Necrosis) at the National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the NIH. Necrosis (Necrotic) Markers, a list of medical indications of necrosis. See also: gangrene Additional definitions from Google and OneLook.

This safety wall poster graphically illustrates the shortcomings of most safety eyewear.

Disclaimer: The information contained herein is believed to be true and accurate, however ILPI makes no guarantees concerning the veracity of any statement. Use of any information on this page is at the reader's own risk. ILPI strongly encourages the reader to consult the appropriate local, state and federal agencies concerning the matters discussed herein.