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Nephrotoxin

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Neurotoxin

Definition

• A neurotoxin is a toxic agent or substance that inhibits, damages or destroys the tissues of the nervous system, especially neurons, the conducting cells of your body's central nervous system. This is an example of a cytotoxin.

Neurotoxic effects can include behavior changes, seizures, as well as wide range of effects, including death. See below.

MSDS Relevance

Both acute and chronic (long and short-term) exposure to certain organic chemicals can cause a variety of health problems including narcosis, anesthesia, CNS (central nervous system) depression, respiratory arrest (heart attack), unconsciousness, coma, and death. See the first link below for more information.

Treat neurotoxins with great respect. The potential for long-lasting or permanent effects from exposure means you should avoid the use of neurotoxins whenever possible. If you must use them, use proper controls to minimize the number of exposed workers (such as fume hoods) as well as respirators, gloves etc.

Further Reading NIOSH has a good article titled Organic Solvent Neurotoxicity. The University of Washingtons' web site "Neuroscience for Kids" has a page on neurotoxins, including lots of info on naturally venomous animals. The U.S. EPA's National Center for Environmental Assessment's Neurotoxicity Guidelines. Read this Centers for Disease Control (CDC) document n-Hexane Related Peripheral Neuropathy Among Automotive Technicians --- California, 1999--2000. See also: cytotoxin, poison, systemic, toxic.

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Disclaimer: The information contained herein is believed to be true and accurate, however ILPI makes no guarantees concerning the veracity of any statement. Use of any information on this page is at the reader's own risk. ILPI strongly encourages the reader to consult the appropriate local, state and federal agencies concerning the matters discussed herein.