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Target Organ Effects

Definition

• Target organ effects indicate which bodily organs are most likely to be affected by exposure to a substance.

Additional Info

The classes of target organ effects are described fully in Appendix A of 29 CFR 1910.1200, an Appendix to the Hazard Communication Standard (HCS) that defines health effects.

MSDS Relevance

When working with chemicals that have target organ effects it is critical to prevent exposure. This is especially true if you have a pre-existing condition, disease or injury to that particular organ. OSHA requires that all hazardous materials be labeled with appropriate hazard warnings, including target organ effects (if known). Some official interpretations include: Definitions of target organ and hazards of chemicals under the Hazard Communication Standard. The HCS's requirement for target organ effects on labels for shipped containers of hazardous chemicals. Clarification of the terms "appropriate hazard warning" and "mandatory". Read the MSDS to determine the most effective personal protective equipment (PPE) for dealing with the chemical and be certain to minimize release of the chemical in the first place.

Safety Emporium carries labels with Target Organ Effect checkboxes and more.

Further Reading

• Target Organ Toxicity at the U of Connecticut has well-organized links to general information about various organs and toxicities.

See also: Health Hazard, RTECS, toxic, and the links in the table of Appendix A.

Additional definitions from Google and OneLook.

Disclaimer: The information contained herein is believed to be true and accurate, however ILPI makes no guarantees concerning the veracity of any statement. Use of any information on this page is at the reader's own risk. ILPI strongly encourages the reader to consult the appropriate local, state and federal agencies concerning the matters discussed herein.